Title:
【発明の名称】弱毒ウイルス
Document Type and Number:
Japanese Patent JPH04502705
Kind Code:
A
Abstract:
An attenuated enterovirus or rhinovirus, suitable for use as a vaccine, has a reversed base pairing in the part, or in a part corresponding to the part, of the 5 min non-coding region of the genome of poliovirus type 3 Leon strain shown below: A suitable attenuated poliovirus has the bases G and C at positions 469 and 534 respectively for a type 1 or type 2 poliovirus or at positions 472 and 537 respectively for a type 3 poliovirus.
Inventors:
Almond, jeffrey, william
Miner, philip, david
Skinner, michael, anthony
Young, Colin, Ruary Duff
Miner, philip, david
Skinner, michael, anthony
Young, Colin, Ruary Duff
Application Number:
JP50236490A
Publication Date:
May 21, 1992
Filing Date:
January 18, 1990
Export Citation:
Assignee:
British Technology Group Limited
International Classes:
A61K39/125; A61K39/13; C12N7/00; C12N7/04; C12N15/00; C12N15/09; C12N15/41; (IPC1-7): A61K39/13; C12N7/01; C12N7/04; C12N15/42
Attorney, Agent or Firm:
Yusuke Hiraki (2 outside)