Title:
【発明の名称】カルバペネム抗菌性化合物、該化合物を含有する組成物及び治療方法
Document Type and Number:
Japanese Patent JP2002516902
Kind Code:
A
Abstract:
The present invention relates to carbapenem antibacterial agents in which the carbapenem nucleus is substituted at the 2 -position with a iodophenoxy linked through a group -Z-CH2-; The compound is further substituted with various substituent groups including at least one cationic group.The compounds are represented by formula I:wherein Z represents trans-ethenediyl or ethynediyl.Pharmaceutical compositions and methods of use are also included.
Inventors:
Frank Pea, Dinino
Kevin Day, Dijkstra
Kevin Day, Dijkstra
Application Number:
JP2000552090A
Publication Date:
June 11, 2002
Filing Date:
May 28, 1999
Export Citation:
Assignee:
Merck End-Campany Inc.
International Classes:
A61K31/397; A61K31/407; A61K31/4995; A61P31/04; C07D477/14; C07D477/00; C07D519/00; C07D519/06; (IPC1-7): C07D477/00; A61K31/407; A61K31/4995; A61P31/04; C07D519/00
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)