Title:
【発明の名称】化学修飾された酵素
Document Type and Number:
Japanese Patent JP2002506342
Kind Code:
A
Abstract:
Modified enzymes are provided in which at least one amino acid, such as asparagine, leucine, methionine or serine, of an enzyme is replaced with a cysteine and the thiol hydrogen is replaced with a substituent group providing a thiol side chain selected from the group consisting of:a) -SR1R2, wherein R1 is an alkyl and R2 is a charged or polar moiety;b) -SR3, wherein R3 is a substituted or unsubstituted phenyl;c) -SR4, wherein R4 is substituted or unsubstituted cyclohexyl;d) -SR5, wherein R5 is C10-C15 alkyl; ande) -SR6 wherein R6 is a C1-6 alkyl.Also, methods of producing the modified enzymes are provided, as well as detergent and feed additives and a composition for the treatment of a textile. A method for using the modified enzymes in organic synthesis is additionally provided. Further, modified enzymes having improved activity, altered pH profile and/or wash performance are provided.
Inventors:
Jones Jay Brian
Bot Richard Earl
Grayker Thomas Peas
Mitchinson Colin
Desantis Grace
Bot Richard Earl
Grayker Thomas Peas
Mitchinson Colin
Desantis Grace
Application Number:
JP52478698A
Publication Date:
February 26, 2002
Filing Date:
November 24, 1997
Export Citation:
Assignee:
Genenco International Inc.
Jones Jay Brian
Jones Jay Brian
International Classes:
C11D3/386; C12N9/00; C12N9/54; C12S3/00; D06M16/00; (IPC1-7): C12N9/00; C11D3/386; C12N9/54; D06M16/00
Attorney, Agent or Firm:
Minoru Nakamura (7 outside)