Title:
【発明の名称】転移誘発性DNA
Document Type and Number:
Japanese Patent JP2000504212
Kind Code:
A
Abstract:
The invention relates to metastasis inducing DNA's, a method of identifying such DNA's and their use in diagnosis and therapy. It includes a method of screening and recovering Met-DNA comprising the steps of: (1) transferring fragments of human DNA from malignant, metastatic cancer cells into a cell line that produces only benign, non-metastasizing tumours when injected into a syngeneic animal; (2) injecting the transformed cells into a syngeneic animal; (3) selecting those animals in which metastasizing tumours have been identified; and (4) recovering the Met-DNA therefrom.
Inventors:
Radland, Philip Spencer
Barraclav, Barry Roger
Barraclav, Barry Roger
Application Number:
JP52499997A
Publication Date:
April 11, 2000
Filing Date:
January 10, 1997
Export Citation:
Assignee:
The University of Liverpool
International Classes:
C12N15/09; A61K31/00; A61K31/70; A61K31/7088; A61P35/00; C12N15/85; C12Q1/68; C12Q1/6886; (IPC1-7): C12N15/09; A61P35/00; A61K31/7088; C12Q1/68
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)