Title:
【発明の名称】ナノカプセル及びその製造方法
Document Type and Number:
Japanese Patent JP2003517998
Kind Code:
A
Abstract:
The invention relates to nanocapsules with a size ranging between 50 nm and 10 mum diameter whose envelope layer consists of at least two different, cross-linked polymers P1 and P2. Optionally, a lipid layer may be present underneath said envelope layer. The inventive nanocapsules are produced by covalently cross-linking at least two different water-soluble polymers P1 and P2 on the surface of liposomes. Optionally, the liposomes are dissolved once the polymers are cross-linked. The inventive nanocapsules can carry biologically active compounds.
Inventors:
Panzner, Sueffen
Application Number:
JP2000582020A
Publication Date:
June 03, 2003
Filing Date:
November 15, 1999
Export Citation:
Assignee:
Novosom AG
International Classes:
A61K9/127; A61K9/50; A61K9/51; A61K47/18; A61K47/26; A61K47/30; A61K47/34; A61K47/42; A61K47/46; G01N33/544; B01J13/02; B01J13/08; B01J13/22; (IPC1-7): A61K9/51; A61K47/18; A61K47/26; A61K47/30; A61K47/34; A61K47/42; A61K47/46; B01J13/08; G01N33/544
Domestic Patent References:
| JPH05112446A | 1993-05-07 | |||
| JPS63501290A | 1988-05-19 | |||
| JPH0912480A | 1997-01-14 | |||
| JPH05505827A | 1993-08-26 | |||
| JPH09221502A | 1997-08-26 | |||
| JPH0853643A | 1996-02-27 | |||
| JPH06178930A | 1994-06-28 | |||
| JPS5417377A | 1979-02-08 | |||
| JPH0214738A | 1990-01-18 | |||
| JPH05154375A | 1993-06-22 |
Other References:
JPN6010024387, ＳＵＮＡＭＯＴＯ，Ｊ． ｅｔ ａｌ, "Ａ ｎｅｗｌｙ ｄｅｖｅｌｏｐｅｄ ｉｍｍｕｎｏｌｉｐｏｓｏｍｅ−−ａｎ ｅｇｇ ｐｈｏｓｐｈａｔｉｄｙｌｃｈｏｌｉｎｅ ｌｉｐｏｓｏｍｅ ｃｏａｔｅｄ ｗｉｔｈ ｐｕｌｌｕｌａｎ ｂｅａｒｉｎｇ ｂ", Ｂｉｏｃｈｉｍ Ｂｉｏｐｈｙｓ Ａｃｔａ, 1987, Ｖｏｌ．８９８， Ｎｏ．３, ｐ．３２３−３０
Attorney, Agent or Firm:
Yusuke Hiraki (1 person outside)