Title:
【発明の名称】ボンベシン様ペプチドに対するレセプター
Document Type and Number:
Japanese Patent JPH06509940
Kind Code:
A
Abstract:
Receptors for bombesin-like peptides are solubilized and purified in active form. The amino acid sequence and DNA encoding various subtypes of the receptors are disclosed. Uses of the purified receptor gene and polypeptide are disclosed, including means for screening for agonists and antagonists of the receptor ligands, for producing diagnostic or therapeutic reagents, and for producing antibodies. Therapeutic or diagnostic reagents and kits are also provided.
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Inventors:
Batty, James F., Jr.
Cojay, Martha H.
Facy, Zara
Feldman, Richard Eye.
Harkin, Richard N.
Threader, Timothy K.
Wada, Etsuko
Wu, James M.
Cojay, Martha H.
Facy, Zara
Feldman, Richard Eye.
Harkin, Richard N.
Threader, Timothy K.
Wada, Etsuko
Wu, James M.
Application Number:
JP51059692A
Publication Date:
November 10, 1994
Filing Date:
March 13, 1992
Export Citation:
Assignee:
Burrex Laboratories, Incorporated
THE UNITED STATES OF AMERICA
THE UNITED STATES OF AMERICA
International Classes:
A61K38/00; A61K39/395; A61P35/00; A61P43/00; C07K14/00; C07K14/705; C07K16/00; C07K16/28; C12N5/10; C12N15/09; C12N15/12; C12P21/02; C12P21/08; C12Q1/68; G01N33/566; C12R1/91; (IPC1-7): C12N15/12; A61K37/02; A61K39/395; C07K13/00; C12N5/10; C12P21/02; C12P21/08; C12Q1/68; G01N33/566
Domestic Patent References:
JP89009232Y |
Attorney, Agent or Firm:
Shoichi Ui (4 others)