Title:
【発明の名称】シクロブテン―3,4―ジオンの置換N―アリールメチルアミノ誘導体
Document Type and Number:
Japanese Patent JP2000513729
Kind Code:
A
Abstract:
The compounds of the formula: wherein R1, R2, R3 and A are as defined herein are useful, via potassium channel modulation, in the treatment of disorders associated with smooth muscle contraction. Such disorders include, but are not limited to, urinary incontinence, hypertension, asthma, premature labor, irritable bowel syndrome, congestive heart failure, angina and cerebral vascular disease.
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Inventors:
Antein, Madeleine Miyoko
Herbst, David Richard
Macfarlane, Geraldine Ruth
Eric Gould, Gundersen
Bradford Hammond, Hearth
Quagliato, Dominique Anthony
Gracefa, Russell Francis
Butera, John Anthony
Gilbert, Adam Matthew
Herbst, David Richard
Macfarlane, Geraldine Ruth
Eric Gould, Gundersen
Bradford Hammond, Hearth
Quagliato, Dominique Anthony
Gracefa, Russell Francis
Butera, John Anthony
Gilbert, Adam Matthew
Application Number:
JP50613698A
Publication Date:
October 17, 2000
Filing Date:
July 16, 1997
Export Citation:
Assignee:
American Home Products Corporation
International Classes:
A61K31/165; A61K31/18; A61K31/27; A61K31/275; A61P9/12; C07C221/00; C07C225/20; C07C233/41; C07C255/58; C07C271/24; A61K31/16; A61K31/00; (IPC1-7): C07C225/20; A61K31/00; A61K31/13; A61K31/16; A61K31/165; A61K31/18; A61K31/27; A61K31/275; C07C221/00; C07C233/41; C07C255/58; C07C271/24
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)