Title:
【発明の名称】アンドロゲン関連疾患の治療方法
Document Type and Number:
Japanese Patent JP3350048
Kind Code:
B2
Abstract:
A method of treatment of androgen-related diseases such as prostate cancer in susceptible male animals, including humans, comprises administering novel antiandrogens and/or novel sex steroid biosynthesis inhibitors as part of a combination therapy. Sex steroid biosynthesis inhibitors, especially those capable of inhibiting conversion of dehydroepiandrosterone (DHEA) or 4-androstenedione ( DELTA 4-dione) to natural sex steroida (and testosterone into dihydrotestosterone) in peripheral tissues, are used in combination with antiandrogens usually after blockade of testicular hormonal secretions. Antiestrogens can also be part of the combination therapy. Pharmaceutical compositions and two, three, four and five component kits are useful for such combination treatment.
Inventors:
Laburi, Fernand
Application Number:
JP50926390A
Publication Date:
November 25, 2002
Filing Date:
July 05, 1990
Export Citation:
Assignee:
ENDORECHERCHE, INC.
International Classes:
A61K31/56; A61K31/565; A61K31/57; A61K31/575; A61K31/58; A61K31/585; A61K31/66; A61K31/695; A61P35/00; A61P43/00; C07J1/00; C07J17/00; C07J41/00; (IPC1-7): A61K31/565; A61K31/57; A61K31/575; A61K31/585; A61K31/66; A61K31/695; A61P35/00; C07J1/00; C07J17/00; C07J41/00
Domestic Patent References:
| JP62500451A |
Other References:
Ｓｔｅｒｏｉｄｓ，４７（１），ｐ．１−１９，１９８６
Attorney, Agent or Firm:
Hisami Fukami (4 outside)