Title:
【発明の名称】新規な縮合チアゾール誘導体,その製造法及びその医薬組成物
Document Type and Number:
Japanese Patent JP2776984
Kind Code:
B2
Abstract:
A condensed thiazole derivative useful as a 5-HT3 receptor agonist, represented by general formula (I), a pharmaceutically acceptable salt thereof, a process for producing the same, and a pharmaceutical composition containing the same, wherein R represents hydrogen, halogen, hydroxy, lower alkoxy, carboxy, lower alkoxycarbonyl, nitro, amino, cyano or protected hydroxy; A represents a benzene or naphthalene ring; one of L1 and L2 represents a mere bond while the other then represents: (a) linear or branched lower alkylene which may be interrupted by oxygen or sulfur, (b) oxygen or sulfur, or (c) lower alkenylene; L represents a mere bond, or linear or branched lower alkylene; Im represents alpha or beta ; R<1>, R<2> and R<3> may be the same or different from one another and each represents hydrogen or lower alkyl; and R<4>, R<5> and R<6> may be the same or different from one another and each represents hydrogen or lower alkyl.
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| WO/1997/016433 | PROTEASE INHIBITORS |
| JPS60136568 | MANUFACTURE OF UREIDE DERIVATIVE |
Inventors:
IWAOKA KYOSHI
KOSHIO HIROYUKI
ITO HIROYUKI
MYATA KEIJI
OOTA MITSUAKI
KOSHIO HIROYUKI
ITO HIROYUKI
MYATA KEIJI
OOTA MITSUAKI
Application Number:
JP50796594A
Publication Date:
July 16, 1998
Filing Date:
September 10, 1993
Export Citation:
Assignee:
YAMANOCHI SEIYAKU KK
International Classes:
A61K31/425; A61K31/428; A61P1/06; A62C2/06; E06B5/12; B21D31/04; B31D1/00; B31D3/04; B31D5/00; B32B3/24; B65D81/02; C07D417/04; C07D417/06; C07D513/04; C07D521/00; E04B1/92; E04H9/00; E04H9/14; E06B9/00; F42D5/045; (IPC1-7): C07D417/06; A61K31/425; C07D417/04; C07D513/04
Domestic Patent References:
| JP311070A | ||||
| JP3255063A | ||||
| JP62252780A | ||||
| JP63243080A | ||||
| JP692404B2 |
Other References:
【文献】国際公開92/9586(WO,A1)
Attorney, Agent or Firm:
Shozo Nagai (1 person outside)