Title:
【発明の名称】大腸菌の増殖に必要であることが同定された遺伝子
Document Type and Number:
Japanese Patent JP2003518386
Kind Code:
A
Abstract:
The sequences of nucleic acids encoding proteins required for E. coli proliferation are disclosed. The nucleic acids can also be used to screen for homologous genes that are required for proliferation in microorganisms other than E. coli. The nucleic acids can also be used to design expression vectors and secretion vectors. The nucleic acids can be used to express proteins or portions thereof, to obtain antibodies capable of specifically binding to the expressed proteins, and to use those expressed proteins as a screen to isolate candidate molecules for rational drug discovery programs. The nucleic acids of the present invention can also be used in various assay systems to screen for antimicrobial agents.
Inventors:
Forsis, Earl Allin
Allsen, Cariel.
Zeiss Kind, Judith W.
Allsen, Cariel.
Zeiss Kind, Judith W.
Application Number:
JP2001548722A
Publication Date:
June 10, 2003
Filing Date:
December 19, 2000
Export Citation:
Assignee:
Eritra Pharmaceuticals, Inc.
International Classes:
G01N33/53; A61K31/7088; A61K45/00; A61K48/00; A61P31/04; A61P31/10; A61P43/00; C07K14/195; C07K14/245; C07K16/12; C12N1/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/31; C12P21/02; C12Q1/02; C12Q1/18; C12Q1/25; G01N33/15; G01N33/566; C12R1/68; (IPC1-7): C12N15/09; A61K31/7088; A61K45/00; A61K48/00; A61P31/04; A61P31/10; A61P43/00; C07K14/195; C07K14/245; C07K16/12; C12N1/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02; C12Q1/02; C12Q1/18; C12Q1/25; G01N33/15; G01N33/53; G01N33/566
Attorney, Agent or Firm:
Tsutomu Toyama (4 others)