トランス-4-((1R,3S)-6-クロロ-3-フェニルインダン-1-イル)-1,2,2-トリメチルピペラジンのコハク酸塩およびマロン酸塩、および薬剤としての使用方法

Title:

トランス-4-((1R,3S)-6-クロロ-3-フェニルインダン-1-イル)-1,2,2-トリメチルピペラジンのコハク酸塩およびマロン酸塩、および薬剤としての使用方法

Document Type and Number:

Japanese Patent JP5043429

Kind Code:

B2

Abstract:

Methods for the preparation of 4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and salts thereof are described.

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Inventors:

Lopez de Diego Haydy
Nielsen Ole
Linkaah Rone Munch
Svane Henrik
Dar Allan Karsten
Hovells Merck
Bank-Andersen Benny
Links Lars Ole

Application Number:

JP2006523528A

Publication Date:

October 10, 2012

Filing Date:

August 18, 2004

Export Citation:

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Assignee:

Her Lundbeck Actiezer Scabet

International Classes:

C07D241/04; A61K31/4965; A61P25/00; A61P25/06; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/30; C07C17/16; C07C25/22; C07C29/143; C07C35/32; C07D295/073; C12P7/22; C12P41/00

Domestic Patent References:

JP7505895A
JP2003509337A
JP2000351773A
JP2003502294A
JP2002517386A
JP2002516314A
JP2001503446A
JP2002531568A
JP6184132A
JP2003502309A

Other References:

Bogeso KP et al,Journal of Medicinal Chemistry,1995年,Vol.38,4380-4392頁
BASTIN,R.J. et al,Salt selection and optimization procedures for pharmaceutical new chemical entities,Organic Process Research & Development,2000年,Vol.4, No.5,p.427-435

Attorney, Agent or Firm:

Mitsufumi Esaki
Blacksmith
Katsunori Uenishi
Ichiro Torayama

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