To provide hormone treatment for control of fertility and as therapy for a variety of diseases and conditions.
A transdermal hormone delivery system (THDS) is disclosed. The THDS is useful for control of fertility and as therapy for a variety of diseases and conditions treatable by robust delivery of progestin and estrogen hormones, particularly the progestin, levonorgestrel. The THDS comprises a backing layer, an adjoining self-adhesive polymer matrix comprising an effective amount of at least a progestin hormone, delivery of which is enhanced by one or more skin permeation enhancing agents present in predetermined amounts. The THDS provides effective daily doses of progestin and estrogen hormones from a small surface area in contact with the skin, e.g. less than 20 cm2. Methods of fertility control and various types of hormone replacement therapy utilizing the THDS are also disclosed.
| JP3066515 | INDUSTRIAL APPLICABILITY: Transdermal preparation for treating urinary incontinence |
| WO/2019/012047 | FAMPRIDINE TTS |
| JPWO2006038315 | Transdermal / transmucosal absorption preparation |
Samejima Mutsumi
Masahiro Nitta
Kure Hidenori
Nobuhiko Akiyama