疾患治療用のカプセルで包んだ生物材料の移植

Japanese Patent JP2006503080

A

Methods of applying biocompatible coating materials around biological materials using photopolymerization while maintaining the pre-encapsulation status of the biological materials are disclosed. The coatings can be placed directly onto the surface of the biological materials or onto the surface of other coating materials that hold the biological materials. The components of the polymerization reactions that produce the coatings can include natural and synthetic polymers, macromers, accelerants, cocatalysts, photoinitiators, and radiation. Methods of utilizing these encapsulated biological materials to treat different human and animal diseases or disorders by implanting them into several areas in the body including the subcutaneous site are also disclosed. The coating materials can be manipulated to provide different degrees of biocompatibility, protein diffusivity characteristics, strength, and biodegradability to optimize the delivery of biological materials from the encapsulated implant to the host recipient while protecting the encapsulated biological materials from destruction by the host inflammatory and immune protective mechanisms without requiring long-term anti-inflammatory or anti-immune treatment of the host.

JP6813491	Cytokine fusion protein
WO/1998/040492	COMPOSITIONS AND METHODS FOR ELIMINATION OF UNWANTED CELLS

David sharp
Paul ratta
Xiao Jie Yu
Cheng Kyun Yue
Jeffrey Hubbell

JP2004543792A

January 26, 2006

October 14, 2003

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Novosel Incorporated

A61K35/12; A61F2/02; A61J3/07; A61K9/50; A61K9/58; A61K35/36; A61K35/39; A61K35/407; A61K35/44; A61K45/00; A61M37/00; A61P1/16; A61P3/10; A61P5/00; A61P7/00; A61P9/00; A61P17/00; A61P25/00; A61P37/00; C12N5/00; C12N5/071; C12N11/08; A61K9/00

Toru Enya

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