TUMOR SPECIFIC ANTIBODY - VIVENTIA BIOTECHNOLOGIES INC

Title:

TUMOR SPECIFIC ANTIBODY

Document Type and Number:

Japanese Patent JP2012187104

Kind Code:

A

Abstract:

To provide human tumor-specific binding proteins, in particular, antibodies or antibody fragments specific for antigens or molecules on cancer cells.

The invention provides an isolated light chain complementarity determining region 1 comprising a specific amino acid sequence or a variant thereof. An immunoconjugate comprising the tumor-specific antibody comprising the region and the tumor-specific antibody attached to a toxin or label can specifically bind to a specific antigen and is used for a medicament for treating or preventing cancer. The tumor-specific antibody is used for diagnosing cancer in mammals.

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Inventors:

GLOVER NICHOLAS RONALD
MACDONALD GLEN CHRISTOPHER
ENTWISTLE JOYCELYN
CIZEAU JEANNICK
BOSC DENIS GEORGES
CHAHAL FRANCINA C

Application Number:

JP2012078467A

Publication Date:

October 04, 2012

Filing Date:

March 30, 2012

Export Citation:

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Assignee:

VIVENTIA BIOTECHNOLOGIES INC

International Classes:

C12N15/09; A61K38/17; A61K39/395; A61K47/48; A61P35/00; C07K14/05; C07K16/30; C07K16/32; C12N15/12; C12N15/13; G01N33/574; A61K38/00; C12P21/08

Attorney, Agent or Firm:

五十嵐義弘
井上隆一
佐藤利光
刑部俊
大関雅人
小林智彦
山口裕孝
川本和弥
新見浩一
春名雅夫
清水初志
渡邉伸一

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