Title:
ULTRAFAST SEQUENCING OF BIOLOGICAL POLYMERS USING LABELED NANOPORE
Document Type and Number:
Japanese Patent JP2016101177
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide methods and systems for sequencing a biological molecule or polymer.SOLUTION: Methods and systems for sequencing a biological molecule or polymer, e.g., a nucleic acid, are provided. One or more donor labels, which are attached to a pore or nanopore, may be illuminated or otherwise excited. A polymer having a monomer labeled with one or more acceptor labels, may be translocated through the pore. Either before, after or while the labeled monomer of the polymer passes through, exits or enters the pore, energy may be transferred from the excited donor label to the acceptor label of the monomer. As a result of the energy transfer, the acceptor label emits energy, and the emitted energy is detected in order to identify the labeled monomer of the translocated polymer to thereby sequence the polymer.SELECTED DRAWING: Figure 3
Inventors:
MARTIN HUBER
Application Number:
JP2016028807A
Publication Date:
June 02, 2016
Filing Date:
February 18, 2016
Export Citation:
Assignee:
QUANTAPORE INC
International Classes:
C12Q1/68; C12M1/00; G01N33/53; G01N33/542; G01N33/543
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita