Title:
超音波増感剤
Document Type and Number:
Japanese Patent JP6940979
Kind Code:
B2
Abstract:
To provide a cancer therapeutic agent, a skin disease therapeutic agent, and an antibacterial agent applicable to an ultrasonic wave chemical therapy.SOLUTION: There are provided a chlorin metal complex represented by the formula (I) or a pharmaceutically acceptable salt thereof, and a therapeutic agent containing them as active ingredients. M is Mn, X is -(CH)-, R is -NHCH-Y, Y is pyridine or methyl pyridinium, n is an integer of 0 to 10, and Z is OAc or Cl.SELECTED DRAWING: None
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Inventors:
Isao Sakata
Toshio Inui
Toshio Inui
Application Number:
JP2017105445A
Publication Date:
September 29, 2021
Filing Date:
May 29, 2017
Export Citation:
Assignee:
Regeneration Pharma Co., Ltd.
International Classes:
C07D487/22; A61K9/06; A61K9/08; A61K9/20; A61K31/555; A61K41/00; A61P17/00; A61P31/04; A61P35/00; A61P43/00
Domestic Patent References:
| JP2014193849A | ||||
| JP6080671A | ||||
| JP2012092024A | ||||
| JP2009263317A |
Foreign References:
| US20100130908 | ||||
| WO2009129321A1 | ||||
| CN107417706A |
Other References:
Wang, Pan et al.,Anti-metastatic and pro-apoptotic effects elicited by combination photodynamic therapy with sonodynamic therapy on breast cancer both in vitro and in vivo,Ultrasonics Sonochemistry,2015年,(2015), 23, 116-127
Brandis, Alexander et al.,Novel water-soluble bacteriochlorophyll derivatives for vascular-targeted photodynamic therapy: Synthesis, solubility, phototoxicity and the effect of serum proteins,Photochemistry and Photobiology,2005年,(2005), 81, 983-993
Brandis, Alexander et al.,Novel water-soluble bacteriochlorophyll derivatives for vascular-targeted photodynamic therapy: Synthesis, solubility, phototoxicity and the effect of serum proteins,Photochemistry and Photobiology,2005年,(2005), 81, 983-993
Attorney, Agent or Firm:
Atomi International Patent Office
Kusama attack
Kusama attack