Title:
痴呆の予防または治療のためのステロイドサポニンの使用、及び新規なステロイドサポニン化合物
Document Type and Number:
Japanese Patent JP4338306
Kind Code:
B2
Abstract:
The invention relates to the steroidal saponin compounds for the propylaxis or treatment dementia, the new steroidal saponin compounds and the pharmaceutical composition containing the same.
Inventors:
Ma bipin
Don, Junxin
One, binge
Don, Junxin
One, binge
Application Number:
JP2000513868A
Publication Date:
October 07, 2009
Filing Date:
September 28, 1998
Export Citation:
Assignee:
Institute of Radiation Medicine, Academy of Military Medical Sciences of the PLA
International Classes:
A61K31/704; A61K31/58; A61P25/28; C07J17/00; C07J43/00; C07J51/00
Other References:
KIMURA, M. et al.,Combined Potentiating Effects of Byako-ka-ninjin-to, Its Constituents, Rhizomes of Anemarrhena asphodeloides, Timosaponin A-III, and Calcium on Pilocarpine-Induced Salvia Secretion in Streptozocin-Diabetic Mice,Biological & Pharmaceutical Bulletin,1996年,Vol.19 , No.7,p.926-931
NAKASHIMA, N. et al.,Isolation of Pseudoprototimosaponin AIII from Rhizomes of Anemarrhena asphodeloides and Its Hypoglycemic Activity in Streptozotocin-Induced Diabetic Mic,J. Nat. Prod.,1993年,Vol.56, No.3 ,pp.345-350
南雲 清二ほか,知母のサポニン成分について,藥學雜誌,1991年,Vol.111 , No.6,pp.306-310
INOUE, T. et al.,Steroidal saponins from the tubers of Dichelostemma multiflorum and their inhibitory activity on cyclic-amp phosphodiesterase,Phytochemistry,1995年,Vol.39, No.5,Pages 1103-1110
LI, X.-C. et al.,Steroidal saponins from Diuranthera major,Phytochemistry ,1990年,Volume 29, Issue 12,Pages 3899-3901
KAWASAKI, T. et al.,Digitalis saponins-IV : Structure of F-gitonin,Tetrahedron,1965年,Volume 21, Issue 3,Pages 299-307
毛利 友二郎,A New Diosgenin Glycoside, Aspidistrin, from Aspidistra elatior BLUME,Chemical & pharmaceutical bulletin ,1973年,Vol.21 , No.1,p.224-227
NL8901732,1991年
杉山 真理ほか,Five Steroidal Components from the Rhizomes of Polygonatum odoratum var. pluriflorum,Chemical & pharmaceutical bulletin ,1984年,Vol.32 , No.4,p.1365-1372
SON, K.H. et al.,Steroidal Saponins from the Rhizomes of Polygonatum sibiricum,J. Nat. Prod.,1990年,Vol.53, No.2,pp 333-339
MA, B. et al.,Studies on the furostanol saponins from Anemarrhea asphodeloides,Yaoxue Xuebao,1996年,Vol.31, No.4,p.271-277
NAKASHIMA, N. et al.,Isolation of Pseudoprototimosaponin AIII from Rhizomes of Anemarrhena asphodeloides and Its Hypoglycemic Activity in Streptozotocin-Induced Diabetic Mic,J. Nat. Prod.,1993年,Vol.56, No.3 ,pp.345-350
南雲 清二ほか,知母のサポニン成分について,藥學雜誌,1991年,Vol.111 , No.6,pp.306-310
INOUE, T. et al.,Steroidal saponins from the tubers of Dichelostemma multiflorum and their inhibitory activity on cyclic-amp phosphodiesterase,Phytochemistry,1995年,Vol.39, No.5,Pages 1103-1110
LI, X.-C. et al.,Steroidal saponins from Diuranthera major,Phytochemistry ,1990年,Volume 29, Issue 12,Pages 3899-3901
KAWASAKI, T. et al.,Digitalis saponins-IV : Structure of F-gitonin,Tetrahedron,1965年,Volume 21, Issue 3,Pages 299-307
毛利 友二郎,A New Diosgenin Glycoside, Aspidistrin, from Aspidistra elatior BLUME,Chemical & pharmaceutical bulletin ,1973年,Vol.21 , No.1,p.224-227
NL8901732,1991年
杉山 真理ほか,Five Steroidal Components from the Rhizomes of Polygonatum odoratum var. pluriflorum,Chemical & pharmaceutical bulletin ,1984年,Vol.32 , No.4,p.1365-1372
SON, K.H. et al.,Steroidal Saponins from the Rhizomes of Polygonatum sibiricum,J. Nat. Prod.,1990年,Vol.53, No.2,pp 333-339
MA, B. et al.,Studies on the furostanol saponins from Anemarrhea asphodeloides,Yaoxue Xuebao,1996年,Vol.31, No.4,p.271-277
Attorney, Agent or Firm:
Kazuo Shamoto
Shosuke Imai
Tadashi Masui
Tadahiko Kurita
Yasushi Kobayashi
Hiroaki Noya
Shosuke Imai
Tadashi Masui
Tadahiko Kurita
Yasushi Kobayashi
Hiroaki Noya