Title:
USING SIZE AND NUMBER ABERRATIONS IN PLASMA DNA FOR DETECTING CANCER
Document Type and Number:
Japanese Patent JP2022191459
Kind Code:
A
Abstract:
To provide systems and methods for determining whether regions exhibit aberration (e.g., amplification or deletion) which may be associated with cancer.SOLUTION: The present invention provides a method of detecting cancer by analyzing size and copy number aberration of circulating cell-free DNA. The method includes parallel sequencing at single base resolution in a genomewide manner. Plasma DNA molecules were further identified using chromosome arm-level z-score analysis.SELECTED DRAWING: Figure 11
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Inventors:
ro yuk-min dennis
Chiurossa Waikun
Chunk Wan Chi
Jian Payon
Chiurossa Waikun
Chunk Wan Chi
Jian Payon
Application Number:
JP2022168977A
Publication Date:
December 27, 2022
Filing Date:
October 21, 2022
Export Citation:
Assignee:
The Chinese University of Hong Kong
International Classes:
C12Q1/6869; C12M1/34; C12N15/11; C12Q1/68
Attorney, Agent or Firm:
Aoki Atsushi
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Ryotaro Takei
Kazumi Nakamura
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Ryotaro Takei
Kazumi Nakamura
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