Title:
8β-ビニル-11β(ω-置換された)アルキル-エストラ-1,3,5(10)-トリエン
Document Type and Number:
Japanese Patent JP2006524202
Kind Code:
A
Abstract:
This invention relates to 8beta-vinyl-11beta-(omega-substituted)alkyl-estra-1,3,5(10)-trienes of general formula I with ERbeta-antagonistic activity, process for their production, their intermediate products, pharmaceutical preparations that contain the compounds according to the invention, as well as their use for the production of pharmaceutical agents. The new compounds can be used for contraception in men and women without influencing other estrogen-sensitive organs such as the uterus or the liver. They are also suitable for treating benign or malignant proliferative diseases of the ovary, such as ovarian cancer and granulosa cell tumors.
Inventors:
Broiel, Nico
Peters, Olaf
Hirish, alexander
Ballman, Rolf
Richter, Margit
Moon,hans peter
Peters, Olaf
Hirish, alexander
Ballman, Rolf
Richter, Margit
Moon,hans peter
Application Number:
JP2006505174A
Publication Date:
October 26, 2006
Filing Date:
April 16, 2004
Export Citation:
Assignee:
Schering Actien Gezel Shaft
International Classes:
C07J1/00; A61K31/56; A61K31/565; A61K31/566; A61K31/567; A61P15/16; A61P15/18; A61P35/00; A61P43/00; C07J3/00; C07J5/00; C07J7/00; C07J75/00; C07J
Foreign References:
| WO2001077138A1 | 2001-10-18 | |||
| WO2001077139A1 | 2001-10-18 |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama
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