Title:
WOUND HEALING COMPOSITION
Document Type and Number:
Japanese Patent JP2015134815
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide compositions and methods for tissue regeneration, particularly for treating skin lesions such as wounds.SOLUTION: In one aspect, the invention provides a wound healing composition comprising living cells such as fibroblasts within a support matrix such as fibrin, in which the cells have a wound healing phenotype, and in which the composition is single layered and has been incubated for up to about 8 days to allow development of the wound healing phenotype. The compositions and methods are useful especially for assisting the process of wound healing, particularly chronic open lesions that are slow to heal or resistant to healing.
Inventors:
KEMP PAUL
TALAS GYOERGYI
SUTHERLAND JENNIFER
BATTEN MARGARET
JOHNSON PENELOPE ANN
SHERING ANDREW
MCWHAN MICHAEL
TALAS GYOERGYI
SUTHERLAND JENNIFER
BATTEN MARGARET
JOHNSON PENELOPE ANN
SHERING ANDREW
MCWHAN MICHAEL
Application Number:
JP2015075997A
Publication Date:
July 27, 2015
Filing Date:
April 02, 2015
Export Citation:
Assignee:
SMITH & NEPHEW ORTHOPAEDICS AG
International Classes:
A61K35/36; A61K9/10; A61K35/34; A61K38/36; A61K47/42; A61L27/00; A61L27/38; A61L27/60; A61P17/02; C12Q1/68; G01N33/569
Domestic Patent References:
| JPH10277143A | 1998-10-20 | |||
| JP2004522545A | 2004-07-29 |
Foreign References:
| US20030165482A1 | 2003-09-04 | |||
| WO2002072113A1 | 2002-09-19 | |||
| WO2002072800A1 | 2002-09-19 |
Other References:
JPN5007001903; ＴＵＡＮ，Ｔ．Ｌ．: ＥＸＰＥＲＩＭＥＮＴＡＬ ＣＥＬＬ ＲＥＳＥＡＲＣＨ Ｖ２２３, 1996, Ｐ１２７-１３４
JPN5007001904; ＭＵＨＡＲＴ，Ｍ．: ＡＲＣＨＩＶＥＳ ＯＦ ＤＥＲＭＡＴＯＬＯＧＹ Ｖ１３５ Ｎ８, 199908, Ｐ９１３-９１８
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JPN6010068014; ＢＲＯＷＮ，Ｌ． ｅｔ ａｌ: Ａｍｅｒｉｃａｎ Ｊｏｕｒｎａｌ ｏｆ Ｐａｔｈｏｌｏｇｙ １４２， １, 1993, ｐ．２７３-２８３
JPN6010068016; ＮＥＩＤＥＲＴ， Ｍ． ｅｔ ａｌ: Ｂｉｏｅｎｇｉｎｅｅｒｉｎｇ Ｃｏｎｆｅｒｅｎｃｅ ５０, 2001, ｐ．２１５-２１６
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Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei