Title:
The biomarkers used for a prediction method of specialization induction potency and a method for the same to a controllable T-lymph cell, and those use
Document Type and Number:
Japanese Patent JP5904801
Kind Code:
B2
Abstract:
A method for predicting differentiation-inducing properties of naive T-cells to regulatory T-cells comprising: measuring an amount of ZAK in naive T-cells contained in the body fluid collected from the living body; and predicting differentiation-inducing properties of the naive T-cells to regulatory T-cells based on the measurement results is disclosed. A method for determining the risk of development of Graft versus Host Disease and a biomarker for predicting differentiation-inducing properties of naive T-cells to regulatory T-cells are also disclosed.
Inventors:
Masatoshi Yanagita
Masakazu Ikeda
Uga Hitoshi
Kurata
Masakazu Ikeda
Uga Hitoshi
Kurata
Application Number:
JP2012007389A
Publication Date:
April 20, 2016
Filing Date:
January 17, 2012
Export Citation:
Assignee:
Sysmex Corporation
International Classes:
C12Q1/68; C12Q1/48
Domestic Patent References:
| JP2009538599A |
Foreign References:
| US20110245090 |
Other References:
Nature Medicine,2008, Vol.14, pp.88-92
日本臨床, 2007, Vol.65, pp.557-567
炎症と免疫,2010, Vol.18, pp.479-483
Biochemical and Biophysical Research Communications,2000, Vol.274, pp.811-816
日本臨床, 2007, Vol.65, pp.557-567
炎症と免疫,2010, Vol.18, pp.479-483
Biochemical and Biophysical Research Communications,2000, Vol.274, pp.811-816
Attorney, Agent or Firm:
Shintaro Nogawa
Shinji Kai
Yusuke Kaneko
Kiyoshi Inamoto
Shinji Kai
Yusuke Kaneko
Kiyoshi Inamoto