Title:
A constituent and a method for treating complement related symptoms
Document Type and Number:
Japanese Patent JP2016537006
Kind Code:
A
Abstract:
本発明は、Ｄ因子阻害剤（例えば抗Ｄ因子抗体又はその抗原結合断片）を用いて様々な補体関連病態（例えばＡＭＤ）を治療するための方法及び組成物を提供する。また提供されるのはＤ因子阻害剤での治療のための患者を選択し又は同定する方法である。方法は予後及び／又は予測バイオマーカーの使用を含む。【選択図】図７
Inventors:
Yaspan, Brian
Graham, Robert Royal
Dressy, amy
Lee, Jeong Long
Strauss, Erich
Bugawan, Theodorica
Graham, Robert Royal
Dressy, amy
Lee, Jeong Long
Strauss, Erich
Bugawan, Theodorica
Application Number:
JP2016533496A
Publication Date:
December 01, 2016
Filing Date:
August 11, 2014
Export Citation:
Assignee:
Genentech, Incorporated
International Classes:
C12Q1/68; A61K39/395; A61P27/02; C12N15/09
Domestic Patent References:
| JP2009514888A | 2009-04-09 | |||
| JP2010508819A | 2010-03-25 | |||
| JP2011521623A | 2011-07-28 |
Other References:
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2012, VOL.53, P.1548-1556, JPN6017010549, ISSN: 0003798603
OPHTHALMOLOGY, 2011, VOL.118, P.2203-2211, JPN6017010552, ISSN: 0003526627
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J MED GENET, 2009, VOL.46, P.300-307, JPN6017010554, ISSN: 0003526628
NATURE GENETICS, APRIL 2013, VOL.45, P.433-441, JPN6017010556, ISSN: 0003526629
PLOS ONE, 2011, VOL.6, E25598, JPN6017010559, ISSN: 0003526630
DATABASE DBSNP [ONLINE], RS4698775, 2004, [検索日:2017.03.21], JPN6017010564, ISSN: 0003526631
DATABASE DBSNP [ONLINE], RS429608, 2003, [検索日:2017.03.21], JPN6017010566, ISSN: 0003526632
DATABASE DBSNP [ONLINE], RS1329428, 2004, [検索日:2017.03.21], JPN6017010567, ISSN: 0003526633
Attorney, Agent or Firm:
Sonoda/Kobayashi Patent Business Corporation