Title:
METHOD FOR ADMINISTRATION OF ANTI-TUMOR AGENT
Document Type and Number:
Japanese Patent JP2017061461
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a dosage regimen which maximizes anti-tumor activity while maintaining acceptable toxicity levels.SOLUTION: A pharmaceutical composition contains a compound A represented by formula (A) as an active ingredient. For the pharmaceutical composition, the compound A in an amount from about 800 to about 3000 mg/day is administered daily for up to about 7 days, followed by a rest period of up to about 21 days, the administration starting on the first day of a 28-day treatment cycle. For the pharmaceutical composition, the treatment cycle is repeated every 28 days for up to about 12 cycles.SELECTED DRAWING: Figure 1
Inventors:
KELLI GLENN
BRIAN HIGGINS
GWEN NICHOLS
KATHRYN E PACKMAN
BRIAN HIGGINS
GWEN NICHOLS
KATHRYN E PACKMAN
Application Number:
JP2016197838A
Publication Date:
March 30, 2017
Filing Date:
October 06, 2016
Export Citation:
Assignee:
HOFFMANN LA ROCHE
International Classes:
A61K31/401; A61P35/00
Attorney, Agent or Firm:
Sonoda/Kobayashi Patent Business Corporation