Title:
A medicine constituent containing a eutectic crystal of piperacillin sodium and sodium sulbactam, a manufacturing method for the same, and the eutectic crystal concerned, and its application
Document Type and Number:
Japanese Patent JP6035420
Kind Code:
B2
Abstract:
Provided in the present invention are a cocrystal of piperacillin sodium and sulbactam sodium and preparation method thereof, as well as pharmaceutical compositions containing the same and uses thereof in treating infections caused by drug-resistant bacteria, such as a "super bacterium" producing NDM-1 and the like. The cocrystal of piperacillin sodium and sulbactam sodium contains diffraction angles of 14.24°, 16.58°, 16.79°, 17.77°, 19.20°, 20.21°, 20.39°, 23.06°, 27.86° and 32.16° represented by 2¸ in an X-ray powder diffraction analysis spectrum.
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| JPS5373592 | PENICILLIN DERIVATIVES |
| JPS5573686 | NOVEL PENICILLIN |
Inventors:
One hyeon
Resin
Resin
Application Number:
JP2015531415A
Publication Date:
November 30, 2016
Filing Date:
September 14, 2012
Export Citation:
Assignee:
Beijing Xintian You Technology Development CEO LTD
International Classes:
C07D499/68; A61K31/43; A61K31/496; A61P31/04; C07D499/86
Domestic Patent References:
| JP2010501493A |
Foreign References:
| CN101632671A | ||||
| CN1167618A | ||||
| WO2008093650A1 | ||||
| CN101912345A |
Attorney, Agent or Firm:
Shigeru Matsui
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