Title:
A new can Nabisi all quinone derivative
Document Type and Number:
Japanese Patent JP6167248
Kind Code:
B2
Abstract:
The present invention relates to novel cannabidiol quinone derivatives of formula (I) (I) wherein R is the carbon atom of a, linear or branched group, represented by: alkyl, aryl, alkenyl, alkynyl, acyl or alkoxycarbonyl groups; or wherein R is the nitrogen atom of a, linear or branched group represented by: alkylamine, arylamine, alkenylamineor alkynylamine groups. The invention also relates to the use of any of the compounds of formula (I)as medicamentsin therapy, particularly for treating diseasesand conditions responsive to PPARg modulationdue to their high PPARg agonistic effect lacking electrophilic (Nrf2 activation) and cytotoxic activities. This invention also provides pharmaceutical compositions comprising said compounds and method of treating diseases with said compounds.
Inventors:
Appendino, Giovanni
Belido Caveyo de Alba, Maria Luz
Muñoz Blanco, Eduardo
Belido Caveyo de Alba, Maria Luz
Muñoz Blanco, Eduardo
Application Number:
JP2016560647A
Publication Date:
July 19, 2017
Filing Date:
April 16, 2014
Export Citation:
Assignee:
Vivacell Biotechnology Espana, S. El.
International Classes:
C07C69/95; A61K31/136; A61K31/235; A61P1/04; A61P1/16; A61P1/18; A61P3/04; A61P3/10; A61P9/10; A61P9/12; A61P13/12; A61P17/00; A61P17/02; A61P17/06; A61P19/02; A61P25/00; A61P25/28; A61P29/00; A61P35/00; A61P43/00; C07C225/28
Domestic Patent References:
| JP2013523623A |
Attorney, Agent or Firm:
Kazuhiro Kiyohara