Title:
17α-アセトキシ-11β-[4-(N、N-ジメチル-アミノ)-フェニル]-19-ノルプレグナ-4,9-ジエン-3,20-ジオンの合成のための工業的プロセスおよびプロセスの新規中間体
Document Type and Number:
Japanese Patent JP2009539964
Kind Code:
A
Abstract:
A new industrial process for the synthesis of solvate-free 17α-acetoxy-11β-[4-(N,N-dimethyl-amino)-phenyl]-19-norpregna-4,9-diene-3,20-dione [CDB-2914] of formula (I) which is a strong antiprogestogene and antiglucocorticoid agent. The invention also relates to compounds of formula (VII) and (VIII) used as intermediates in the process.
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| JPH04145024 | BONE RESORPTION SUPPRESSING AGENT |
| WO/1995/012402 | ESTROGEN COMPOSITIONS AND METHOD FOR NEUROPROTECTION |
Inventors:
Dunch, Rayosune
Viskey, gerje
Brim, zoltan
Corgay, Janos
Molnar, Chaba
Majari, Endrene
Viskey, gerje
Brim, zoltan
Corgay, Janos
Molnar, Chaba
Majari, Endrene
Application Number:
JP2009514916A
Publication Date:
November 19, 2009
Filing Date:
May 18, 2007
Export Citation:
Assignee:
Richter Gedeon Nirvanoshan Miquedeles Vental Shashag
International Classes:
C07J1/00; A61K31/567; A61K31/569; A61K31/57; A61K31/58; A61P5/24; A61P5/46; C07J5/00; C07J13/00; C07J21/00
Foreign References:
| WO2004078709A2 | 2004-09-16 | |||
| WO2004101594A1 | 2004-11-25 | |||
| US4041055A | 1977-08-09 |
Other References:
JPN6012047538; ＶＡＮＲＨＥＥＮＥＮ，Ｖ． ｅｔ ａｌ: Ｊ． Ｏｒｇ． Ｃｈｅｍ． Ｖｏｌ．４４， Ｎｏ．９, 1979, ｐ．１５８２-４
Attorney, Agent or Firm:
Haruo Hamada