PHENYL C-GLUCOSIDE DERIVATIVE HAVING DEOXYGLUCOSE STRUCTURE, AND METHODS OF PREPARATION AND USE THEREOF

Title:

PHENYL C-GLUCOSIDE DERIVATIVE HAVING DEOXYGLUCOSE STRUCTURE, AND METHODS OF PREPARATION AND USE THEREOF

Document Type and Number:

Japanese Patent JP2016188220

Kind Code:

A

Abstract:

PROBLEM TO BE SOLVED: To provide sodium glucose cotransporter 2 (SGLT2) inhibitors which have a therapeutic effect on diabetes, and preparation methods thereof.SOLUTION: The invention provides a phenyl C-glucoside derivative having a deoxyglucose structure represented by the formula (I-D1-6).SELECTED DRAWING: None

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Inventors:

ZHAO GUILONG
WANG YULI
LIU BINGNI
XIE YAFEI
LIU YUQIANG
LIU PENG
WU JIANG
HOU JIAJIA
WEI WEI
DU WEN
XU WEIREN
TANG LIDA
ZOU MEIXIANG

Application Number:

JP2016102380A

Publication Date:

November 04, 2016

Filing Date:

May 23, 2016

Export Citation:

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Assignee:

TIANJIN INST PHARM RES

International Classes:

C07D309/06; A61K31/35; A61K31/351; A61K31/381; A61K31/382; A61K31/7048; A61P3/10; A61P43/00; C07D309/10; C07D335/02; C07D407/12; C07D409/10; C07D493/10; C07H7/04

Domestic Patent References:

JP2008505146A	2008-02-21
JP2008514668A	2008-05-08
JP2009538339A	2009-11-05
JP2007518683A	2007-07-12
JP2012500842A	2012-01-12

Foreign References:

WO2006073197A1

2006-07-13

Other References:

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. Vol.20(5), JPN6015049516, 2010, pages 1569 - 72, ISSN: 0003628915

Attorney, Agent or Firm:

Hisashi Kato
Keita Tohsaka
Hiroshi Mori
Toru Minase

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