Title:
A phenyl ester side chain for improving the absorbency of polymer
Document Type and Number:
Japanese Patent JP6046331
Kind Code:
B2
Abstract:
The present invention relates to polymers modified to increase their resorbability. In particular, the polymers of the invention have phenyl ester side chains which are good leaving groups and which thereby increase the resorption rate of the polymer relative to the same polymer, for example, bearing a comparable amount of an alkyl ester side chain. Such polymers are generally water insoluble, but when modified are able to solubilize drugs and upon degradation and resorption, release those in a physiological environment in a controlled and/or sustained manner.
Inventors:
Schwartz, Arthur
Pura Pura, Satish
Nesara, Sarita
Pura Pura, Satish
Nesara, Sarita
Application Number:
JP2010513454A
Publication Date:
December 14, 2016
Filing Date:
June 20, 2008
Export Citation:
Assignee:
TYRX INC.
International Classes:
C08G63/193; A61K31/085; A61K31/496; A61K31/65; A61K31/7036; A61K38/00; A61K47/34; A61L27/00; A61L31/00; A61L33/00; A61P1/00; A61P7/02; A61P9/00; A61P9/10; A61P25/00; A61P27/02; C07C235/34
Domestic Patent References:
| JP2000501139A | ||||
| JP2006520217A | ||||
| JP2001514618A |
Foreign References:
| WO2007056134A2 |
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito