Title:
スタフィロコッカス・アウレウス(STAPHYLOCOCCUSAUREUS)に対する防御免疫応答を誘導するポリペプチド
Document Type and Number:
Japanese Patent JP2012509665
Kind Code:
A
Abstract:
The present invention features polypeptides comprising an amino acid sequence structurally related to SEQ ID NO: 1 and uses of such polypeptides and compositions thereof. SEQ ID NO: 1 is a full length S. aureus sequence. A derivative of SEQ ID NO: 1 containing an amino terminus his-tag was found to produce a protective immune response against S. aureus.
Inventors:
Matsu Cleanie, Tessie Bee
Corp, Leslie Day
Mirror, Mark A
Schulz, Lauren Day
Wang, Shin Min
Corp, Leslie Day
Mirror, Mark A
Schulz, Lauren Day
Wang, Shin Min
Application Number:
JP2011537574A
Publication Date:
April 26, 2012
Filing Date:
November 18, 2009
Export Citation:
Assignee:
Merck Sharp End Dome Corporation
International Classes:
C12N15/09; A61K39/085; A61K39/39; A61P11/00; A61P17/00; A61P17/10; A61P19/00; A61P19/02; A61P25/00; A61P27/02; A61P31/04; A61P37/04; C07K14/31; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02
Attorney, Agent or Firm:
Yoshikazu Iwase
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Yasufumi Shiroyama
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Yasufumi Shiroyama