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Title:
髄膜炎菌(Neisseria Meningitidis)のプロテイナーゼK抵抗性表面蛋白質
Document Type and Number:
Japanese Patent JPH11500624
Kind Code:
A
Abstract:
A highly conserved, immunologically accessible antigen at the surface of Neisseria meningitides organisms. Immunotherapeutic, prophylactic and diagnostic compositions and methods useful in the treatment, prevention and diagnosis of Neisseria meningitidis diseases. A proteinase K resistant Neisseria meningitidis surface protein having an apparent molecular weight of 22 kDa, the corresponding nucleotide and derived amino acid sequences (SEQ ID NO:1, NO:3, NO:5 and NO:7; SEQ ID NO:2, NO:4, NO:6 and NO:8), recombinant DNA methods for the production of the Neisseria meningitidis 22 kDa surface protein, and antibodies that bind to the Neisseria meningitidis 22 kDa surface protein

Inventors:
ハメル ジョゼ
ブロデゥール バーナード アール.
マーティン デニス
リオックス クレモント
Application Number:
JP52792896A
Publication Date:
January 19, 1999
Filing Date:
March 15, 1996
Export Citation:
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Assignee:
バイオケム ヴァシーンズ インク.
International Classes:
A61K39/095; A61K39/395; A61K39/40; A61K49/00; A61P31/04; A61P43/00; C07K14/195; C07K14/22; C07K16/12; C12N1/21; C12N15/02; C12N15/09; C12N15/16; C12N15/31; C12N15/70; C12P19/34; C12P21/02; C12P21/08; G01N33/53; C12Q1/04; C12Q1/68; G01N33/15; G01N33/531; G01N33/564; G01N33/566; G01N33/569; G01N33/577; A61K38/00; A61K39/00; C12R1/01; C12R1/19; C12R1/36; C07K; (IPC1-7): C12N15/09; A61K39/095; A61K39/395; A61K49/00; C07K14/22; C07K16/12; C12N1/21; C12N15/02; C12P21/02; C12P21/08; C12Q1/04; C12Q1/68; G01N33/15; G01N33/531; G01N33/569
Attorney, Agent or Firm:
清水 初志 (外1名)