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Title:
A therapeutic method of the vendor Mustin response condition in the patient who needs the reduced medication capacity
Document Type and Number:
Japanese Patent JP6224064
Kind Code:
B2
Abstract:
Methods of treating bendamustine responsive conditions in patients having fluid and/or sodium intake restrictions are disclosed. The methods include identifying patients having such restrictions and in need of bendamustine, and then administering thereto a bendamustine-containing composition in a volume of about 120 ml or less intravenously over a period of about 15 minutes or less. The smaller volumes and reduced sodium load as compared to currently known methods of treatment minimize cardiac and/or renal stress in patients having diseases such as congestive heart failure or renal disease.

Inventors:
Sundalam, Srikans
Tariff, Scott, Elle.
Application Number:
JP2015501814A
Publication Date:
November 01, 2017
Filing Date:
March 15, 2013
Export Citation:
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Assignee:
Eagle Pharmaceuticals Incorporated
International Classes:
A61K31/4184; A61K9/08; A61K47/02; A61K47/10; A61K47/20; A61P35/00; A61P35/02
Domestic Patent References:
JP2013518130A
JP2008505966A
Foreign References:
US20110184036
WO2007026771A1
Other References:
HIGHLIGHT OF PRESCRIBING INFORMATION (TREANDA),2008年,pp.1-11
日本医薬品集 医療薬(2004年度版) ,株式会社じほう ,2003年10月25日,pp.186-188、1089、2298-2299、2421
医薬品添加物事典 2007,株式会社薬事日報社,2007年,pp.242-243、279-280
Haematologica. 2005, Vol.90, No.10, pp.1357-1364
Cancer Sci., 2010,Vol.101,No.9, pp.2054-2058
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Naoko Kikuta