2-AMINO-3-ALKOXYBICYCLO[3.1.0]HEXANE DERIVATIVE

Title:

2-AMINO-3-ALKOXYBICYCLO[3.1.0]HEXANE DERIVATIVE

Document Type and Number:

WIPO Patent Application WO/2005/000789

Kind Code:

A1

Abstract:

A drug which is effective in treatments for and prevention of schizophrenia, anxiety, and diseases related to these, i.e., psychiatrical disorders such as depression, bipolar disorder, and epilepsy. The drug has an antagonistic effect on a Group II metabotropic glutamate receptor. It is a 2-amino-3-alkoxybicyclo[3.1.0]hexane-2,6dicarboxylic acid derivative represented by the formula [I]: [I] (wherein R¹ and R² are the same or different and each represents hydrogen, C_1-10 alkyl, etc.; and R³ represents naphthyl or phenyl substituted by one to five substituents selected from the group consisting of cyano, phenyl, and halogeno and R⁴ represents hydrogen, C_1-10 alkyl, etc., or R³ and R⁴ each represents phenyl), a pharmaceutically acceptable salt of the derivative, or a hydrate of either.

More Like This:

JP4447661	Plant extract for the treatment of increased bone resorption
JP2022536982	Targeting α3β1 integrins for the treatment of cancer and other diseases
WO/2022/013706	A PROCESS FOR THE PREPARATION OF L-GLUTAMINE

Inventors:

YASUHARA AKITO (JP)
SAKAGAMI KAZUNARI (JP)
OHTA HIROSHI (JP)
NAKAZATO ATSURO (JP)

Application Number:

PCT/JP2004/009365

Publication Date:

January 06, 2005

Filing Date:

June 25, 2004

Export Citation:

Click for automatic bibliography generation Help

Assignee:

TAISHO PHARMACEUTICAL CO LTD (JP)
YASUHARA AKITO (JP)
SAKAGAMI KAZUNARI (JP)
OHTA HIROSHI (JP)
NAKAZATO ATSURO (JP)

International Classes:

A61K31/198; A61K31/216; A61K31/277; A61P1/06; A61P1/08; A61P9/00; A61P25/08; A61P25/14; A61P25/16; A61P25/22; A61P25/24; A61P25/28; A61P25/30; C07C229/50; C07C255/54; (IPC1-7): C07C229/50; C07C255/54; A61K31/198; A61K31/216; A61K31/277; A61P1/06; A61P1/08; A61P9/00; A61P25/08; A61P25/14; A61P25/16; A61P25/22; A61P25/24; A61P25/28; A61P25/30

Foreign References:

JP2000086597A	2000-03-28
JP2000336071A	2000-12-05
JPH0361698A	1991-03-18

Attorney, Agent or Firm:

Kobayashi, Hiroshi c/o Abe (Ikubo & Katayama Fukuoka Bldg. 9th Fl., 8-7, Yaesu 2-chom, Chuo-ku Tokyo 28, JP)

Download PDF:

View/Download PDF PDF Help

Previous Patent: METHOD FOR DEHYDRATING SUBSTITUTED 4-DIMETHYLAMINO-2-ARYL-BUTAN-2-OL COMPOUNDS AND METHOD FOR PRODUC...

Next Patent: PROCESS FOR PRODUCING N-ACYLATED AMINO ACID DERIVATIVE