Title:
3-(BIS-SUBSTITUTED-PHENYLMETHYLENE)OXINDOLE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/1997/026242
Kind Code:
A1
Abstract:
Oxindole derivatives represented by general formula (1) and drugs containing the same, wherein R represents methyl or methoxy. Because of having excellent effects of inhibiting granulation with little hepatic toxicity, these compounds are useful as drugs and usable in the prevention and treatmeent of articular rheumatism, arterial sclerosis, hepatic cirrhosis, arthrosis deformans, psoriasis, gout, nephritis, angiitis, inflammatory enteral diseases (ulcerative colitis, Crohn's disease), bronchitis, arthritis, chronic granulomatous disease, etc.
Inventors:
SATO ATSUSHI (JP)
ASAO TETSUJI (JP)
HAGIWARA YUICHI (JP)
KITADE MAKOTO (JP)
YAMAZAKI YASUNDO (JP)
ASAO TETSUJI (JP)
HAGIWARA YUICHI (JP)
KITADE MAKOTO (JP)
YAMAZAKI YASUNDO (JP)
Application Number:
PCT/JP1997/000066
Publication Date:
July 24, 1997
Filing Date:
January 16, 1997
Export Citation:
Assignee:
TAIHO PHARMACEUTICAL CO LTD (JP)
SATO ATSUSHI (JP)
ASAO TETSUJI (JP)
HAGIWARA YUICHI (JP)
KITADE MAKOTO (JP)
YAMAZAKI YASUNDO (JP)
SATO ATSUSHI (JP)
ASAO TETSUJI (JP)
HAGIWARA YUICHI (JP)
KITADE MAKOTO (JP)
YAMAZAKI YASUNDO (JP)
International Classes:
C07D209/34; C07D401/06; C07D401/14; C07D471/04; (IPC1-7): C07D209/34; A61K31/40
Foreign References:
| JPS433195B1 | ||||
| JPS60222415A | 1985-11-07 |
Other References:
See also references of EP 0816338A4
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