Title:
7H-PYRROLO[2,3-D]PYRIMIDINE-4-AMINE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2020/166680
Kind Code:
A1
Abstract:
The present invention provides a novel compound inhibiting EGFR or a salt of the compound. According to one embodiment of the present invention, provided is a compound represented by general formula (I) or a pharmaceutically acceptable salt thereof.
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Inventors:
YAMAMOTO FUYUKI (JP)
MIZUTANI TAKASHI (JP)
KASUGA HIDEFUMI (JP)
FUCHIDA HIROKAZU (JP)
HARA SHOKI (JP)
KOBAYAKAWA YU (JP)
OGINO YOSHIO (JP)
MIZUTANI TAKASHI (JP)
KASUGA HIDEFUMI (JP)
FUCHIDA HIROKAZU (JP)
HARA SHOKI (JP)
KOBAYAKAWA YU (JP)
OGINO YOSHIO (JP)
Application Number:
PCT/JP2020/005684
Publication Date:
August 20, 2020
Filing Date:
February 14, 2020
Export Citation:
Assignee:
TAIHO PHARMACEUTICAL CO LTD (JP)
International Classes:
A61P35/00; A61K31/519; A61K31/53; A61K31/5377; C07D487/04; C07D519/00
Domestic Patent References:
| WO2013118817A1 | 2013-08-15 | |||
| WO2015178955A1 | 2015-11-26 | |||
| WO2014078578A1 | 2014-05-22 | |||
| WO2007075554A2 | 2007-07-05 | |||
| WO2013118817A1 | 2013-08-15 | |||
| WO2018079310A1 | 2018-05-03 |
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"All Cancers", INTERNATIONAL AGENCY FOR RESEARCH ON CANCER, 2018, Retrieved from the Internet>
LUNG CANCER, vol. 69, 2010, pages 1 - 12
NATURE REV. CANCER, vol. 10, 2010, pages 760 - 774
ESMO OPEN, vol. 1, 2016, pages e000060
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CHEMICAL REVIEWS, vol. 107, 2007, pages 874
CHEMICAL REVIEWS, vol. 95, 1995, pages 2457
SYNTHETIC COMMUNICATIONS, vol. 19, pages 561
T. W. GREENE: "Protective Groups in Organic Synthesis", 1981, JOHN WILEY & SONS
"GenBan", Database accession no. NP _005219.2
"GenBank", Database accession no. NP_005219.2
See also references of EP 3925669A4
CURRENT OPINION IN ONCOLOGY, vol. 13, 2001, pages 506 - 513
"All Cancers", INTERNATIONAL AGENCY FOR RESEARCH ON CANCER, 2018, Retrieved from the Internet
LUNG CANCER, vol. 69, 2010, pages 1 - 12
NATURE REV. CANCER, vol. 10, 2010, pages 760 - 774
ESMO OPEN, vol. 1, 2016, pages e000060
J. CLIN. ONCOL., vol. 36, 2018, pages 841 - 849
CHEMICAL REVIEWS, vol. 107, 2007, pages 874
CHEMICAL REVIEWS, vol. 95, 1995, pages 2457
SYNTHETIC COMMUNICATIONS, vol. 19, pages 561
T. W. GREENE: "Protective Groups in Organic Synthesis", 1981, JOHN WILEY & SONS
"GenBan", Database accession no. NP _005219.2
"GenBank", Database accession no. NP_005219.2
See also references of EP 3925669A4
Attorney, Agent or Firm:
KOBAYASHI Hiroshi et al. (JP)
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