Title:
ANTIBODY AGAINST HUMAN $g(a)1,3-FUCOSE TRANSFERASE Fuc-TVII
Document Type and Number:
WIPO Patent Application WO/1999/048926
Kind Code:
A1
Abstract:
An antibody reacting with human $g(a)1,3-fucose transferase (Fuc-TVII); a method for immunologically detecting and quantitating human $g(a)1,3-fucose transferase (Fuc-TVII) by using the above antibody; and drugs and methods for diagnosing cancer, inflammatory diseases or allergic diseases with the use of the antibody.
Inventors:
SHITARA KENYA (JP)
KAWADA YOKO (JP)
YOSHIHARA YUKO (JP)
OHTA SO (JP)
HANAI NOBUO (JP)
SASAKI KATSUTOSHI (JP)
KAWADA YOKO (JP)
YOSHIHARA YUKO (JP)
OHTA SO (JP)
HANAI NOBUO (JP)
SASAKI KATSUTOSHI (JP)
Application Number:
PCT/JP1999/001483
Publication Date:
September 30, 1999
Filing Date:
March 24, 1999
Export Citation:
Assignee:
KYOWA HAKKO KOGYO KK (JP)
SHITARA KENYA (JP)
KAWADA YOKO (JP)
YOSHIHARA YUKO (JP)
OHTA SO (JP)
HANAI NOBUO (JP)
SASAKI KATSUTOSHI (JP)
SHITARA KENYA (JP)
KAWADA YOKO (JP)
YOSHIHARA YUKO (JP)
OHTA SO (JP)
HANAI NOBUO (JP)
SASAKI KATSUTOSHI (JP)
International Classes:
C07K16/40; C12P21/08; G01N33/573; (IPC1-7): C07K16/40; A61K39/395; C07K16/46; C12N5/12; C12N9/10; C12N15/02; C12P21/08; G01N33/573; G01N33/577
Domestic Patent References:
| WO1997032889A1 | 1997-09-12 | |||
| WO1994023021A1 | 1994-10-13 |
Other References:
REITER Y., ET AL.: "ENGINEERING INTERCHAIN DISULFIDE BONDS INTO CONSERVED FRAMEWORK REGIONS OF FV FRAGMENTS: IMPROVED BIOCHEMICAL CHARACTERISTICS OF RECOMBINANT IMMUNOTOXINS CONTAINING DISULFIDE-STABILIZED FV.", PROTEIN ENGINEERING, OXFORD UNIVERSITY PRESS, SURREY., GB, vol. 07., no. 05., 1 May 1994 (1994-05-01), GB, pages 697 - 704., XP000443154, ISSN: 0269-2139
TRAIL P. A., ET AL.: "CURE OF XENOGRAFTED HUMAN CARCINOMAS BY BR96-DOXORUBICIN IMMUNOCONJUGATES.", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, vol. 261., no. 5118., 9 July 1993 (1993-07-09), US, pages 212 - 215., XP002920991, ISSN: 0036-8075, DOI: 10.1126/science.8327892
DEACON T., ET AL.: "HISTOLOGICAL EVIDENCE OF FETAL PIG NEURAL CELL SURVIVAL AFTER TRANSPLANTATION INTO A PATIENT WITH PARKINSON'S DISEASE.", NATURE MEDICINE., NATURE PUBLISHING GROUP, NEW YORK, NY., US, vol. 03., no. 03., 1 March 1997 (1997-03-01), US, pages 350 - 353., XP002920992, ISSN: 1078-8956, DOI: 10.1038/nm0397-350
HANSKI C., ET AL.: "FUCOSYLTRANSFERASE III AND SIALYL-LEX EXPRESSION CORRELATE IN CULTURED COLON CARCINOMA CELLS BUT NOT IN COLON CARCINOMA TISSUE.", GLYCOCONJUGATE JOURNAL, CHAPMAN & HALL, BOSTON, vol. 13., no. 05., 1 January 1996 (1996-01-01), Boston, pages 727 - 733., XP002920993, ISSN: 0282-0080, DOI: 10.1007/BF00702336
CLARKE J. L., WATKINS W. M.: "ALPHA1,3-L-FUCOSYLTRANSFERASE EXPRESSION IN DEVELOPING HUMAN MYELOID CELLS.", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, vol. 271., no. 17., 26 April 1996 (1996-04-26), US, pages 10317 - 10328., XP002920994, ISSN: 0021-9258, DOI: 10.1074/jbc.271.17.10317
TRAIL P. A., ET AL.: "CURE OF XENOGRAFTED HUMAN CARCINOMAS BY BR96-DOXORUBICIN IMMUNOCONJUGATES.", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, vol. 261., no. 5118., 9 July 1993 (1993-07-09), US, pages 212 - 215., XP002920991, ISSN: 0036-8075, DOI: 10.1126/science.8327892
DEACON T., ET AL.: "HISTOLOGICAL EVIDENCE OF FETAL PIG NEURAL CELL SURVIVAL AFTER TRANSPLANTATION INTO A PATIENT WITH PARKINSON'S DISEASE.", NATURE MEDICINE., NATURE PUBLISHING GROUP, NEW YORK, NY., US, vol. 03., no. 03., 1 March 1997 (1997-03-01), US, pages 350 - 353., XP002920992, ISSN: 1078-8956, DOI: 10.1038/nm0397-350
HANSKI C., ET AL.: "FUCOSYLTRANSFERASE III AND SIALYL-LEX EXPRESSION CORRELATE IN CULTURED COLON CARCINOMA CELLS BUT NOT IN COLON CARCINOMA TISSUE.", GLYCOCONJUGATE JOURNAL, CHAPMAN & HALL, BOSTON, vol. 13., no. 05., 1 January 1996 (1996-01-01), Boston, pages 727 - 733., XP002920993, ISSN: 0282-0080, DOI: 10.1007/BF00702336
CLARKE J. L., WATKINS W. M.: "ALPHA1,3-L-FUCOSYLTRANSFERASE EXPRESSION IN DEVELOPING HUMAN MYELOID CELLS.", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, vol. 271., no. 17., 26 April 1996 (1996-04-26), US, pages 10317 - 10328., XP002920994, ISSN: 0021-9258, DOI: 10.1074/jbc.271.17.10317
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