Title:
ABHD6 ANTAGONIST
Document Type and Number:
WIPO Patent Application WO/2024/071398
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a drug for the prevention and/or treatment of diseases associated with ABHD6, said drug containing a compound having ABHD6 inhibitory activity as an active ingredient. A compound represented by general formula (I) (in the formula, all symbols have the same meanings as the symbols described in the description) or a pharmaceutically acceptable salt thereof has ABHD6 inhibitory activity, and is therefore useful as a drug component having potent ABHD6 inhibitory activity in the prevention and/or treatment of diseases associated with ABHD6.
Inventors:
YOSHIDA ATSUSHI (JP)
HYAKUTAKE RYUICHI (JP)
NAGASHIMA NOZOMU (JP)
MISU RYOSUKE (JP)
MORI SHOHEI (JP)
HYAKUTAKE RYUICHI (JP)
NAGASHIMA NOZOMU (JP)
MISU RYOSUKE (JP)
MORI SHOHEI (JP)
Application Number:
PCT/JP2023/035690
Publication Date:
April 04, 2024
Filing Date:
September 29, 2023
Export Citation:
Assignee:
ONO PHARMACEUTICAL CO (JP)
International Classes:
C07D495/04; A61K31/501; A61K31/5025; A61P25/00; A61P25/02; A61P25/22; A61P25/24; A61P43/00; C07D409/14; C07D417/14; C07D513/04; C07D519/00
Domestic Patent References:
| WO2022211060A1 | 2022-10-06 | |||
| WO2021080015A1 | 2021-04-29 | |||
| WO2021048036A1 | 2021-03-18 |
Other References:
DENG HUI; LI WEIMIN: "Therapeutic potential of targeting α/β-Hydrolase domain-containing 6 (ABHD6)", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, ELSEVIER, AMSTERDAM, NL, vol. 198, 25 April 2020 (2020-04-25), AMSTERDAM, NL , XP086167144, ISSN: 0223-5234, DOI: 10.1016/j.ejmech.2020.112353
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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