Title:
ABIDOR HYDROCHLORIDE TABLET AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2023/070985
Kind Code:
A1
Abstract:
Disclosed are an abidor hydrochloride tablet and a preparation method therefor. The abidor hydrochloride tablet comprises the following components in parts by mass: 40-60 parts of abidor hydrochloride, 60-90 parts of a soybean phospholipid, 45-75 parts of a tea polyphenol, 86-120 parts of a filler, 4-15 parts of a disintegrant and 3-9 parts of a lubricant. By compounding the soybean phospholipid with the tea polyphenol, the solubility of abidor hydrochloride is improved, and by adding the disintegrant, the filler and the lubricant and preparing the abidor hydrochloride into tablets, the disintegration effect of the tablets is improved and the dissolution of abidor hydrochloride is significantly promoted, thereby helping to improve the efficacy of abidor hydrochloride tablets.
Inventors:
SUN LIJIE (CN)
LI LEI (CN)
CHENG YANCHAO (CN)
DONG WEICHANG (CN)
DING LIXIU (CN)
ZUO YUE (CN)
ZHAO WENHE (CN)
LI LEI (CN)
CHENG YANCHAO (CN)
DONG WEICHANG (CN)
DING LIXIU (CN)
ZUO YUE (CN)
ZHAO WENHE (CN)
Application Number:
PCT/CN2022/075623
Publication Date:
May 04, 2023
Filing Date:
February 09, 2022
Export Citation:
Assignee:
SHIJIAZHUANG NO 4 PHARM CO LTD (CN)
International Classes:
A61K9/20; A61K9/28; A61K31/4045; A61K47/22; A61K47/24; A61P31/16
Foreign References:
| CN113842370A | 2021-12-28 | |||
| CN101653425A | 2010-02-24 | |||
| CN112933043A | 2021-06-11 | |||
| CN101904826A | 2010-12-08 | |||
| CN102413829A | 2012-04-11 | |||
| CN112933061A | 2021-06-11 | |||
| CN101066248A | 2007-11-07 |
Other References:
HAO, HAIJUN ET AL.: "Progress in Research on Enhancing Dissolution and Bioavailability of Chinese Materia Medica-Phospholipid Complex with New Preparation Techniques", CHINESE TRADITIONAL AND HERBAL DRUGS, vol. 44, no. 17, 30 September 2013 (2013-09-30), pages 2474 - 2479, XP009545323, ISSN: 0253-2670
PINGALI PRASUNA SUNDARI, PRATHIMA SRINIVAS AND B. MADHAVA REDDY: "MICONAZOLE LOADED NOVEL PHYTOSOMAL TOPICAL GELS", WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES, vol. 4, no. 10, 1 January 2015 (2015-01-01), BG , pages 2305 - 2320, XP093062465, ISSN: 2278-4357
KUCHE, K. ET AL.: "Drug-Phospholipid Complex—a Go Through Strategy for Enhanced Oral Bioavailability.", AAPS PHARMSCITECH, vol. 20, no. 2, 4 January 2019 (2019-01-04), XP036699281, ISSN: 1530-9932, DOI: 10.1208/s12249-018-1252-4
PINGALI PRASUNA SUNDARI, PRATHIMA SRINIVAS AND B. MADHAVA REDDY: "MICONAZOLE LOADED NOVEL PHYTOSOMAL TOPICAL GELS", WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES, vol. 4, no. 10, 1 January 2015 (2015-01-01), BG , pages 2305 - 2320, XP093062465, ISSN: 2278-4357
KUCHE, K. ET AL.: "Drug-Phospholipid Complex—a Go Through Strategy for Enhanced Oral Bioavailability.", AAPS PHARMSCITECH, vol. 20, no. 2, 4 January 2019 (2019-01-04), XP036699281, ISSN: 1530-9932, DOI: 10.1208/s12249-018-1252-4
Attorney, Agent or Firm:
HEBEI GUOWEIZHIYUAN INTELLECTUAL PROPERTY AGENCY CO., LTD (CN)
Download PDF:
Previous Patent: HEAVY CROSS OVERPASS OF AXIS RING ROAD TRUNK LINE
Next Patent: FERROELECTRIC TUNNEL JUNCTION DEVICE AND MANUFACTURING METHOD THEREFOR
Next Patent: FERROELECTRIC TUNNEL JUNCTION DEVICE AND MANUFACTURING METHOD THEREFOR