Title:
AGENT FOR AMELIORATING EYESTRAIN
Document Type and Number:
WIPO Patent Application WO/2015/199203
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide an agent for preventing or ameliorating eyestrain. Provided is an agent for preventing or ameliorating eyestrain, said agent comprising citrulline or a salt thereof as an active ingredient.
Inventors:
KUMAGAI KOTA (JP)
MORITA MASAHIKO (JP)
KAMIMURA AYAKO (JP)
MORITA MASAHIKO (JP)
KAMIMURA AYAKO (JP)
Application Number:
PCT/JP2015/068428
Publication Date:
December 30, 2015
Filing Date:
June 25, 2015
Export Citation:
Assignee:
KYOWA HAKKO BIO CO LTD (JP)
International Classes:
A61K31/198; A61P27/02
Domestic Patent References:
| WO2008004333A1 | 2008-01-10 | |||
| WO2013001786A1 | 2013-01-03 |
Foreign References:
| JP2012051821A | 2012-03-15 | |||
| JP2008208041A | 2008-09-11 | |||
| JP2002226370A | 2002-08-14 |
Other References:
TAKEDA, K. ET AL.: "Effects of citrulline supplementation on fatigue and exercise performance in mice", J. NUTR. SCI. VITAMINOL., vol. 57, no. 3, 2011, pages 246 - 250, XP055248757
PEREZ-GUISADO, J. ET AL.: "Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness", J. STRENGTH COND. RES., vol. 24, no. 5, 2010, pages 1215 - 1222
WU, RE. ET AL.: "Resveratrol protects against physical fatigue and improves exercise performance in mice", MOLECULES, vol. 18, no. 4, 2013, pages 4689 - 4702, XP055248759
SAWAKI, K. ET AL.: "Sports Performance Benefits from Taking Natural Astaxanthin Characterized by Visual Acuity and Muscle Fatigue Improvement in Humans", JOURNAL OF CLINICAL THERAPEUTICS & MEDICINES, vol. 18, no. 9, 2002, pages 1085 - 1100
AKASHI, K. ET AL.: "Citrulline, a novel compatible solute in drought-tolerant wild watermelon leaves, is an efficient hydroxyl radical scavenger", FEBS LETT., vol. 508, no. 3, 2001, pages 438 - 442, XP004324285, ISSN: 0014-5793
PEREZ-GUISADO, J. ET AL.: "Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness", J. STRENGTH COND. RES., vol. 24, no. 5, 2010, pages 1215 - 1222
WU, RE. ET AL.: "Resveratrol protects against physical fatigue and improves exercise performance in mice", MOLECULES, vol. 18, no. 4, 2013, pages 4689 - 4702, XP055248759
SAWAKI, K. ET AL.: "Sports Performance Benefits from Taking Natural Astaxanthin Characterized by Visual Acuity and Muscle Fatigue Improvement in Humans", JOURNAL OF CLINICAL THERAPEUTICS & MEDICINES, vol. 18, no. 9, 2002, pages 1085 - 1100
AKASHI, K. ET AL.: "Citrulline, a novel compatible solute in drought-tolerant wild watermelon leaves, is an efficient hydroxyl radical scavenger", FEBS LETT., vol. 508, no. 3, 2001, pages 438 - 442, XP004324285, ISSN: 0014-5793
Attorney, Agent or Firm:
Eikoh Patent Firm, P. C. et al. (JP)
Patent business corporation glory patent firm (JP)
Patent business corporation glory patent firm (JP)
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