Title:
AGENT AND PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING JOINT DISEASE
Document Type and Number:
WIPO Patent Application WO/2023/149020
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a novel treatment agent and/or preventative agent for joint disease. The present invention provides an agent for treating and/or preventing joint disease containing, as an active ingredient, one or more miRNA selected from the group consisting of hsa-mir-1199-5p, hsa-mir-1246, hsa-mir-1290, hsa-mir-141-5p, and hsa-mir-4700-5p. The present invention also provides a pharmaceutical composition for treating and/or preventing joint disease containing the agent for treating and/or preventing joint disease.
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Inventors:
KATO MIKI (JP)
SATO MASATO (JP)
SATO MASATO (JP)
Application Number:
PCT/JP2022/038131
Publication Date:
August 10, 2023
Filing Date:
October 12, 2022
Export Citation:
Assignee:
TOKAI UNIV EDUCATIONAL SYSTEM (JP)
International Classes:
A61K9/08; A61K31/7105; A61K9/14; A61K47/46; A61K48/00; A61P19/02; A61P29/00; A61P43/00; C12N15/113; C12N15/88
Domestic Patent References:
| WO2018071806A1 | 2018-04-19 | |||
| WO2010001632A1 | 2010-01-07 |
Foreign References:
| JP2020171299A | 2020-10-22 |
Other References:
DIEPENBRUCK MAREN, TIEDE STEFANIE, SAXENA MEERA, IVANEK ROBERT, KALATHUR RAVI KIRAN REDDY, LÜÖND FABIANA, MEYER-SCHALLER NATHALIE,: "miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis", NATURE COMMUNICATIONS, vol. 8, no. 1, XP093082837, DOI: 10.1038/s41467-017-01197-w
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
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