Title:
AMINE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2004/024672
Kind Code:
A1
Abstract:
The invention relates to (1S)-1-isobutoxymethyl-3- methylbutylamine useful as an intermediate in the synthesis of sodium (2S, 3S)-3-[[(1S)-1-isobutoxymethyl-3-methylbutyl]- carbamoyl]oxirane-2-carboxylate and a process for production thereof. The process comprises reacting L-leucinol with a compound represented by the following general formula: [wherein X is a leaving group] in the presence of a base and reducing the obtained (1S)-1-(2-methyl-2-propenoxymethyl)-3-methylbutylamine.
Inventors:
TENDO ATSUSHI (JP)
TAKAHASHI TOSHIHIRO (JP)
YAMAKAWA TOMIO (JP)
TAKAHASHI TOSHIHIRO (JP)
YAMAKAWA TOMIO (JP)
Application Number:
PCT/JP2003/011468
Publication Date:
March 25, 2004
Filing Date:
September 09, 2003
Export Citation:
Assignee:
NIPPON CHEMIPHAR CO (JP)
TENDO ATSUSHI (JP)
TAKAHASHI TOSHIHIRO (JP)
YAMAKAWA TOMIO (JP)
TENDO ATSUSHI (JP)
TAKAHASHI TOSHIHIRO (JP)
YAMAKAWA TOMIO (JP)
International Classes:
C07C29/06; C07C211/02; C07C213/08; C07C217/08; (IPC1-7): C07C213/08; C07C217/08
Domestic Patent References:
| WO1999011640A1 | 1999-03-11 |
Other References:
See also references of EP 1538142A4
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