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Title:
AMPHIPHILIC DERIVATIVES FOR THE PRODUCTION OF VESICLES, MICELLES AND COMPLEXANTS, AND PRECURSORS THEREOF
Document Type and Number:
WIPO Patent Application WO2002055011
Kind Code:
A3
Abstract:
Amphiphilic derivatives composed of at least one fatty acid chain are derived from natural vegetable oils such as vernonia oil, lesquerella oil and castor oil, in which the several reactive groups such as epoxy, hydroxy and double bonds can be modified to polar and ionic groups. The head group of the amphiphilic derivative may be in the main fatty acid chain or in a side chain. The amphiphiles are useful for the formation of vesicles and micelles and for use as complexants and surfactants.

Inventors:
GRINBERG SARINA (IL)
LINDER CHARLES (IL)
WIESMAN ZEEV (IL)
HELDMAN ELIAHU (IL)
KOLOT VICTORIA (IL)
Application Number:
PCT/IL2002/000043
Publication Date:
February 27, 2003
Filing Date:
January 16, 2002
Export Citation:
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Assignee:
UNIV BEN GURION (IL)
GRINBERG SARINA (IL)
LINDER CHARLES (IL)
WIESMAN ZEEV (IL)
HELDMAN ELIAHU (IL)
KOLOT VICTORIA (IL)
International Classes:
C07D303/42; A61K9/127; A61K47/18; A61K47/24; C07C69/675; C07C69/732; C07C229/12; C07C229/16; C07C229/22; C07C229/30; C07C235/28; C07C247/12; C07C301/00; C07D303/04; C07D303/46; C07F9/655; A61K9/107; (IPC1-7): C07C69/76
Domestic Patent References:
WO1997014713A11997-04-24
WO1998042898A11998-10-01
Foreign References:
US5434307A1995-07-18
US5530148A1996-06-25
Other References:
See also references of EP 1360168A4
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