Title:
ANTI-CD3ΓΕ ANTIBODY AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/150762
Kind Code:
A1
Abstract:
The present invention relates to: an antibody against CD3γε or an antigen-binding fragment thereof; a nucleic acid encoding same; a vector comprising the nucleic acid; cells transformed with the vector; a method for preparing the antibody or the antigen-binding fragment thereof; a composition for preventing or treating T cell-mediated diseases, comprising same; and a method for treating T cell-mediated diseases.
Inventors:
KIM SUN TAEK (KR)
RYU GI HYUCK (KR)
KIM HYE JIN (KR)
PARK SANG RAE (KR)
JUNG HYUN HO (KR)
YANG GI HYEOK (KR)
RYU GI HYUCK (KR)
KIM HYE JIN (KR)
PARK SANG RAE (KR)
JUNG HYUN HO (KR)
YANG GI HYEOK (KR)
Application Number:
PCT/KR2016/003357
Publication Date:
September 08, 2017
Filing Date:
March 31, 2016
Export Citation:
Assignee:
MEDYTOX INC (KR)
International Classes:
C07K16/28; A61K39/395; A61P35/00; A61P37/00; C12N15/13; C12N15/63; C12P21/08
Domestic Patent References:
| WO2015181098A1 | 2015-12-03 |
Foreign References:
| US20140141020A1 | 2014-05-22 | |||
| US20140066600A1 | 2014-03-06 |
Other References:
DATABASE NCBI [O] 3 August 2017 (2017-08-03), "Chain A, Crystal Structure Of Cd3gammaepsilon Heterodimer In Complex With Okt3 Fab Fragment", XP055414571, Database accession no. 1SY6_A
KJER-NIELSEN ET AL.: "Crystal Structure of the Human T Cell Receptor CD 3 epsilon gamma Heterodimer Complexed to the Therapeutic mAb OKT3", PNAS, vol. 101, no. 20, 2004, pages 7675 - 7680, XP055329073
KJER-NIELSEN ET AL.: "Crystal Structure of the Human T Cell Receptor CD 3 epsilon gamma Heterodimer Complexed to the Therapeutic mAb OKT3", PNAS, vol. 101, no. 20, 2004, pages 7675 - 7680, XP055329073
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
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