Title:
ANTI-BRAIN-TUMOR DRUG
Document Type and Number:
WIPO Patent Application WO/2011/135784
Kind Code:
A1
Abstract:
Disclosed is a drug that contains as the primary component a metal-salen complex compound that is effective against brain tumors. The anti-brain-tumor drug contains a metal-salen complex compound represented by the belowmentioned chemical formula (I). In the formula, M is a metal atom comprising Fe, Cr, Mn, Co, Ni, Mo, Ru, Rh, Pd, W, Re, Os, Ir, Pt, Nd, Sm, Eu, or Gd, and X is a halogen atom.
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Inventors:
ISHIKAWA YOSHIHIRO (JP)
EGUCHI HARUKI (JP)
EGUCHI HARUKI (JP)
Application Number:
PCT/JP2011/002118
Publication Date:
November 03, 2011
Filing Date:
April 11, 2011
Export Citation:
Assignee:
IHI CORP (JP)
ISHIKAWA YOSHIHIRO (JP)
EGUCHI HARUKI (JP)
ISHIKAWA YOSHIHIRO (JP)
EGUCHI HARUKI (JP)
International Classes:
A61K31/555; A61P35/00; C07C251/24; C07F15/02
Domestic Patent References:
| WO2010058280A1 | 2010-05-27 |
Foreign References:
| JPH11507646A | 1999-07-06 | |||
| JPH08504211A | 1996-05-07 | |||
| JP2009173631A | 2009-08-06 | |||
| JP2009173631A | 2009-08-06 |
Other References:
See also references of EP 2564852A4
ACCELRYS K.K.: "COSMO-RS: From Quantum Chemistry to Fluid Phase Thermodynamics and Drug Design", 2005, ELSEVIER, article "The energy of water solubility was calculated by a method by Andreas Klamt"
ACCELRYS K.K.: "COSMO-RS: From Quantum Chemistry to Fluid Phase Thermodynamics and Drug Design", 2005, ELSEVIER, article "The energy of water solubility was calculated by a method by Andreas Klamt"
Attorney, Agent or Firm:
OHGA, Shinji et al. (JP)
Shinji Oga (JP)
Shinji Oga (JP)
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Claims: