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Title:
ANTI-CD33 ANTIBODIES AND METHODS OF USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/201389
Kind Code:
A3
Abstract:
The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a CD33 protein, e.g. , human CD33 or a mammalian CD33, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.

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Inventors:
ROSENTHAL ARNON (US)
MONROE KATE (US)
AVOGADRI-CONNORS FRANCESCA (US)
Application Number:
PCT/US2016/037109
Publication Date:
February 02, 2017
Filing Date:
June 11, 2016
Export Citation:
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Assignee:
ALECTOR LLC (US)
International Classes:
C07K16/28; A61K39/00; C07K16/00
Domestic Patent References:
WO2012045752A12012-04-12
Foreign References:
CN102952191A2013-03-06
Other References:
ERIKA A EKSIOGLU ET AL: "Novel Therapeutic Approach to Improve Hematopoiesis By Targeting Myeloid Derived Suppressor Cells with a Humanized Anti-CD33 Antibody", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 124, 1 January 2014 (2014-01-01), pages 4597, XP009191679, ISSN: 0006-4971
SUTHERLAND MAY KUNG ET AL: "Anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia", MABS, LANDES BIOSCIENCE, US, vol. 1, no. 5, 1 September 2009 (2009-09-01), pages 481 - 490, XP009142398, ISSN: 1942-0862
Attorney, Agent or Firm:
ZHOU, Jie et al. (US)
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