ANTI-HUMAN CXCL1 ANTIBODY - CHIOME BIOSCIENCE INC

Title:

ANTI-HUMAN CXCL1 ANTIBODY

Document Type and Number:

WIPO Patent Application WO/2023/145844

Kind Code:

A1

Abstract:

Provided is a substance demonstrating an anti-tumor effect by introducing changes in a tumor microenvironment (TME), including inhibition or suppression of TME formation. This invention relates to an anti-human CXCL1 antibody including designated CDR sequences, or an antibody fragment thereof.

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Inventors:

YASHIRO MASAKAZU (JP)
YAMAMOTO YURIE (JP)
YOSHIOKA AKIKO (JP)
NAKAMURA KOJI (JP)
YANAI HIROYUKI (JP)
INOUE TOSHIKAZU (JP)

Application Number:

PCT/JP2023/002533

Publication Date:

August 03, 2023

Filing Date:

January 26, 2023

Export Citation:

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Assignee:

CHIOME BIOSCIENCE INC (JP)
UNIV OSAKA PUBLIC CORP (JP)

International Classes:

C07K16/18; A61K39/395; A61K45/00; A61P1/00; A61P35/00; A61P43/00; C12N15/13

Domestic Patent References:

WO2020160022A1

2020-08-06

Foreign References:

JP2016528170A	2016-09-15
JP2017206447A	2017-11-24

Other References:

MAKITO MIYAKE, HIDEKI FURUYA, SAYURI ONISHI, KANANI HOKUTAN, SATOSHI ANAI, OWEN CHAN, SIXIANG SHI, KIYOHIDE FUJIMOTO, STEVE GOODIS: "Monoclonal Antibody against CXCL1 (HL2401) as a Novel Agent in Suppressing IL6 Expression and Tumoral Growth", THERANOSTICS, IVYSPRING INTERNATIONAL PUBLISHER, AU, vol. 9, no. 3, 1 January 2019 (2019-01-01), AU , pages 853 - 867, XP055615177, ISSN: 1838-7640, DOI: 10.7150/thno.29553

Attorney, Agent or Firm:

KOBAYASHI Hiroshi et al. (JP)

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