Title:
ANTI-NOROVIRUS ANTIBODY
Document Type and Number:
WIPO Patent Application WO/2022/244861
Kind Code:
A1
Abstract:
Disclosed is an anti-norovirus antibody that reacts with noroviruses of many genotypes and makes it possible to collectively detect noroviruses. The anti-norovirus antibody or an antigen-binding fragment thereof performs an antigen-antibody reaction with individual peptides comprising the amino acid sequences indicated in each of SEQ ID NO: 1 and SEQ ID NO: 2. The present invention provides: a novel anti-norovirus antibody that binds widely to noroviruses and makes it possible to widely detect human noroviruses specifically and with high sensitivity; and a norovirus immunoassay method and a norovirus immunoassay tool in which the anti-norovirus antibody is used.
Inventors:
SAITO YUJI (JP)
HIRAOKA KOJI (JP)
OGASAWARA SHINYA (JP)
HIRAOKA KOJI (JP)
OGASAWARA SHINYA (JP)
Application Number:
PCT/JP2022/020945
Publication Date:
November 24, 2022
Filing Date:
May 20, 2022
Export Citation:
Assignee:
DENKA COMPANY LTD (JP)
International Classes:
C07K16/10; C12M1/34; C12Q1/02; G01N33/569; C07K14/08; C12N15/13; C12P21/08
Domestic Patent References:
| WO2002040509A1 | 2002-05-23 | |||
| WO2013039165A1 | 2013-03-21 |
Foreign References:
| JP2002020399A | 2002-01-23 | |||
| JP2009542715A | 2009-12-03 |
Other References:
MALM MARIA, TAMMINEN KIRSI, VESIKARI TIMO, BLAZEVIC VESNA: "Type-specific and cross-reactive antibodies and T cell responses in norovirus VLP immunized mice are targeted both to conserved and variable domains of capsid VP1 protein", MOLECULAR IMMUNOLOGY, PERGAMON, GB, vol. 78, 1 October 2016 (2016-10-01), GB , pages 27 - 37, XP093008691, ISSN: 0161-5890, DOI: 10.1016/j.molimm.2016.08.009
"Evaluation of an improved norovirus antigen detection EIA kit", JAPANESE JOURNAL OF MEDICINE AND PHARMACEUTICAL SCIENCE, vol. 61, no. 1, 25 January 2009 (2009-01-25), pages 93 - 98
"Evaluation of the QuickNavi-Noro quick norovirus antigen diagnosing agent", JAPANESE JOURNAL OF MEDICINE AND PHARMACEUTICAL SCIENCE, vol. 61, no. 5, 25 May 2009 (2009-05-25), pages 779 - 785
GABRIEL I. PARRA ET AL., PLOS ONE, vol. 8, June 2013 (2013-06-01), pages e67592
KOHLER ET AL., NATURE, vol. 256, 1975, pages 495 - 497
JOSEPHY P.D.MASON R.P. ET AL., J. BIOL. CHEM., vol. 257, 1982, pages 3669 - 3675
"Evaluation of an improved norovirus antigen detection EIA kit", JAPANESE JOURNAL OF MEDICINE AND PHARMACEUTICAL SCIENCE, vol. 61, no. 1, 25 January 2009 (2009-01-25), pages 93 - 98
"Evaluation of the QuickNavi-Noro quick norovirus antigen diagnosing agent", JAPANESE JOURNAL OF MEDICINE AND PHARMACEUTICAL SCIENCE, vol. 61, no. 5, 25 May 2009 (2009-05-25), pages 779 - 785
GABRIEL I. PARRA ET AL., PLOS ONE, vol. 8, June 2013 (2013-06-01), pages e67592
KOHLER ET AL., NATURE, vol. 256, 1975, pages 495 - 497
JOSEPHY P.D.MASON R.P. ET AL., J. BIOL. CHEM., vol. 257, 1982, pages 3669 - 3675
Attorney, Agent or Firm:
TANIGAWA AND PARTNERS, PATENT FIRM (JP)
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