Title:
ANTI-NOVEL CORONAVIRUS COMPLEX AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2021/253807
Kind Code:
A1
Abstract:
Provided is an anti-novel coronavirus complex and a preparation method therefor. The complex is composed of an immunostimulant wrapped by a recombinant anti-novel coronavirus alpaca nanobody-coupled liposome. Said immunostimulant is encapsulated in the recombinant nanobody-coupled liposome.
Inventors:
TAN XIANGSHI (CN)
PEI JIANWU (CN)
ZHANG YUERU (CN)
XIANG DAOFENG (CN)
PEI JIANWU (CN)
ZHANG YUERU (CN)
XIANG DAOFENG (CN)
Application Number:
PCT/CN2020/142599
Publication Date:
December 23, 2021
Filing Date:
December 31, 2020
Export Citation:
Assignee:
HANGZHOU XINGAO BIOTECHNOLOGY CO LTD (CN)
International Classes:
A61K39/395; A61K47/54; A61K47/69; A61P31/14
Domestic Patent References:
| WO2015028888A2 | 2015-03-05 | |||
| WO2002059154A2 | 2002-08-01 |
Foreign References:
| CN108310378A | 2018-07-24 | |||
| CN106540256A | 2017-03-29 |
Other References:
DANIEL WRAPP, DE VLIEGER DORIEN, CORBETT KIZZMEKIA S., TORRES GRETEL M., WANG NIANSHUANG, VAN BREEDAM WANDER, ROOSE KENNY, VAN SCH: "Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies", CELL, ELSEVIER, AMSTERDAM NL, vol. 181, no. 5, 28 May 2020 (2020-05-28), Amsterdam NL , pages 1004 - 1015.e15, XP055764639, ISSN: 0092-8674, DOI: 10.1016/j.cell.2020.04.031
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