Title:
ANTI-TETANUS TOXIN NEUTRALIZING ANTIBODY, PREPARATION METHOD THEREFOR, AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/128121
Kind Code:
A1
Abstract:
Disclosed is an anti-tetanus toxin neutralizing body, the preparation, and uses thereof. The antibody can be used for preventing, treating and diagnosing tetanus infection and/or treating one or more symptoms of Clostridium tetani-mediated infection. Also provided is a method for producing an antibody that immunospecifically binds to a tetanus toxin.
Inventors:
LIAO HUAXIN (CN)
WANG YUEMING (CN)
YUAN XIAOHUI (CN)
WANG YUEMING (CN)
YUAN XIAOHUI (CN)
Application Number:
PCT/CN2018/090491
Publication Date:
July 04, 2019
Filing Date:
June 08, 2018
Export Citation:
Assignee:
ZHUHAI TRINOMAB BIOTECHNOLOGY CO LTD (CN)
GUANGZHOU TRINOMAB BIOTECHNOLOGY CO LTD (CN)
GUANGZHOU TRINOMAB BIOTECHNOLOGY CO LTD (CN)
International Classes:
C07K16/12; A61K39/40; C12N15/13; C12N15/63
Foreign References:
| CN1634991A | 2005-07-06 | |||
| CN105153305A | 2015-12-16 | |||
| CN102206275A | 2011-10-05 | |||
| CN102875674A | 2013-01-16 | |||
| EP0562132A1 | 1993-09-29 | |||
| JPH0257195A | 1990-02-26 | |||
| KR100624011B1 | 2006-09-19 |
Other References:
MEIJER, P.J.: "Isolation of Human Antibody Repertoires with Preservation of the Natural Heavy and Light Chain Pairing", J. MOL. BIOL., 2 March 2006 (2006-03-02), XP024950964
MEIJER, P.J., AY866984.1: HOMO SAPIENS CLONE 60A02 ANTI-TETANUS TOXOID IMMUNOGLOBULIN LIGHT CHAIN VARIABLE REGION (IGL@) MRNA, PARTIAL CDS, 26 July 2016 (2016-07-26)
MEIJER, P.J., AY866984.1: HOMO SAPIENS CLONE 60A02 ANTI-TETANUS TOXOID IMMUNOGLOBULIN LIGHT CHAIN VARIABLE REGION (IGL@) MRNA, PARTIAL CDS, 26 July 2016 (2016-07-26)
Attorney, Agent or Firm:
BEIJING MIZAR STAR INTELLECTUAL PROPERTY AGENCY (CN)
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