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Title:
ANTIBODIES, RECOMBINANT ANTIBODIES, RECOMBINANT ANTIBODY FRAGMENTS AND FUSIONS MEDIATED PLANT DISEASE RESISTANCE AGAINST FUNGI
Document Type and Number:
WIPO Patent Application WO2003089475
Kind Code:
A3
Abstract:
A method for the production of fungus resistant transgenic plants, plant cells or plant tissue comprising the introduction of an Ab, rAb, rAb fragment or fusion or vector of the invention or the vectors of the composition of the invention into the genome of a plant, plant cell or plant cell tissue and a transgenic plant cell comprising stably integrated into the genome a polynucleotide or vector of the invention or the vectors of the composition of the invention.

Inventors:
PESCHEN DIETER (DE)
FISCHER RAINER (DE)
SCHILLBERG STEFAN (DE)
LIAO YU-CAI (DE)
DORFMUELLER SIMONE (DE)
Application Number:
PCT/EP2003/003852
Publication Date:
June 03, 2004
Filing Date:
April 14, 2003
Export Citation:
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Assignee:
FRAUNHOFER GES FORSCHUNG (DE)
PESCHEN DIETER (DE)
FISCHER RAINER (DE)
SCHILLBERG STEFAN (DE)
LIAO YU-CAI (DE)
DORFMUELLER SIMONE (DE)
International Classes:
C07K16/14; C07K19/00; C12N15/13; C12N15/62; C12N15/82; (IPC1-7): C07K19/00; A01H1/00; C07K14/79; C07K16/14; C12N5/10; C12N9/24; C12N15/13; C12N15/62; C12N15/82
Domestic Patent References:
WO2000023593A22000-04-27
WO1996009398A11996-03-28
WO1996000783A11996-01-11
Foreign References:
US6087560A2000-07-11
Other References:
LIAO YU CAI ET AL: "Characterization of a wheat class Ib chitinase gene differentially induced in isogenic lines by infection with Puccinia graminis.", PLANT SCIENCE (LIMERICK), vol. 103, no. 2, Q41539, 1994, pages 177 - 187, XP009017155, ISSN: 0168-9452, Retrieved from the Internet
PESCHEN D: "SYNTHETIC CONSTRUCT FOR ANTI-FUSARIUM SCFV ANTIBODY, CLONE CWP2", EMBL, 29 November 2002 (2002-11-29), XP002253955
GROVER ANITA ET AL: "Removal of vacuolar targeting signal from class I vacuolar chitinase leads to its extracellular secretion in transgenic tobacco", JOURNAL OF PLANT BIOCHEMISTRY AND BIOTECHNOLOGY, vol. 10, no. 2, July 2001 (2001-07-01), pages 139 - 142, XP009024181, ISSN: 0971-7811
GAN ZHIBO ET AL: "The characterization of chicken antibodies raised against Fusarium spp. by enzyme-linked immunosorbent assay and immunoblotting", INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 38, no. 2-3, 1997, pages 191 - 200, XP002254389, ISSN: 0168-1605
SCHOUTEN A ET AL: "THE C-TERMINAL KDEL SEQUENCE INCREASES THE EXPRESSION LEVEL OF A SINGLE-CHAIN ANTIBODY DESIGNED TO BE TARGETED TO BOTH THE CYTOSOL AND THE SECRETORY PATHWAY IN TRANSGENIC TOBACCO", PLANT MOLECULAR BIOLOGY, NIJHOFF PUBLISHERS, DORDRECHT, NL, vol. 30, 1996, pages 781 - 793, XP000677225, ISSN: 0167-4412
TAVLADORAKI P ET AL: "TRANSGENIC PLANTS EXPRESSING A FUNCTIONAL SINGLE-CHAIN FV ANTIBODY SPECIFICALLY P ROTECTED FROM VIRUS ATTACK", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 366, 2 December 1993 (1993-12-02), pages 469 - 472, XP000421325, ISSN: 0028-0836
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