Title:
ANTIBODY AGAINST SARS-COV-2
Document Type and Number:
WIPO Patent Application WO/2024/019110
Kind Code:
A1
Abstract:
The present invention provides a novel antibody having high binding affinity and infection neutralizing activity against classic SARS-CoV-2 (Wuhan strain) and also other variants, including the omicron strain. Provided is an antibody against SARS-CoV-2, the antibody being characterized by binding to a spike glycoprotein receptor binding domain (RBD) of SARS-CoV-2, and recognizing serine 443 or tyrosine 489 of the amino acid sequence of the spike glycoprotein.
More Like This:
| WO/2005/012538 | ACCELERATED VACCINATION |
| WO/2023/064435 | COMPOSITIONS AND METHODS RELATING TO SARS-COV-2 NEUTRALIZING ANTIBODIES |
| WO/2020/124846 | NEUTRALIZING ANTIBODY AGAINST RESPIRATORY SYNCYTIAL VIRUS AND USE THEREOF |
Inventors:
TAKAHASHI YOSHIMASA (JP)
MORIYAMA SAYA (JP)
YUMOTO KOUHEI (JP)
KURODA DAISUKE (JP)
ADACHI YU (JP)
MORIYAMA SAYA (JP)
YUMOTO KOUHEI (JP)
KURODA DAISUKE (JP)
ADACHI YU (JP)
Application Number:
PCT/JP2023/026565
Publication Date:
January 25, 2024
Filing Date:
July 20, 2023
Export Citation:
Assignee:
JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF NAT INSTITUTE OF INFECTIOUS DISEASES (JP)
International Classes:
C07K16/10; A61K39/395; A61P31/14; G01N33/569; C12N15/13; C12P21/08
Domestic Patent References:
| WO2021195418A1 | 2021-09-30 | |||
| WO2022065445A1 | 2022-03-31 | |||
| WO2022095968A1 | 2022-05-12 | |||
| WO2022053188A1 | 2022-03-17 | |||
| WO2022003530A1 | 2022-01-06 | |||
| WO2021244601A1 | 2021-12-09 |
Foreign References:
| US20220204591A1 | 2022-06-30 |
Other References:
DUAN XIAOMIN, SHI RUI, LIU PULAN, HUANG QINGRUI, WANG FENGZE, CHEN XINYU, FENG HUI, HUANG WEIJIN, XIAO JUNYU, YAN JINGHUA: "A non-ACE2-blocking neutralizing antibody against Omicron-included SARS-CoV-2 variants", SIGNAL TRANSDUCTION AND TARGETED THERAPY, vol. 7, no. 1, 1 January 2022 (2022-01-01), XP093130068, ISSN: 2059-3635, DOI: 10.1038/s41392-022-00879-2
DATABASE PDB 19 July 2023 (2023-07-19), ANONYMOUS : "SARS-CoV-2 spike in complex with neutralizing antibody NIV-8 (state 2)", XP093130075, retrieved from RCSB Database accession no. 7YH7
DATABASE PDB 19 July 2023 (2023-07-19), ANONYMOUS : "SARS-CoV-2 spike in complex with neutralizing antibody NIV-8 (state 2)", XP093130075, retrieved from RCSB Database accession no. 7YH7
Attorney, Agent or Firm:
NOMURA, Kenichi et al. (JP)
Download PDF:
Previous Patent: CONTROL DEVICE, CONTROL METHOD, AND PROGRAM
Next Patent: LEVELING AGENT FOR COATING MATERIAL, AND COATING MATERIAL COMPOSITION
Next Patent: LEVELING AGENT FOR COATING MATERIAL, AND COATING MATERIAL COMPOSITION